| Year |
Citation |
Score |
| 2020 |
Pous L, Deshpande SS, Nath S, Mezey S, Malik SC, Schildge S, Bohrer C, Topp K, Pfeifer D, Fernández-Klett F, Doostkam S, Galanakis DK, Taylor V, Akassoglou K, Schachtrup C. Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling. Nature Communications. 11: 630. PMID 32005867 DOI: 10.1038/S41467-020-14466-Y |
0.361 |
|
| 2019 |
Borjini N, Paouri E, Tognatta R, Akassoglou K, Davalos D. Imaging the dynamic interactions between immune cells and the neurovascular interface in the spinal cord. Experimental Neurology. 113046. PMID 31472115 DOI: 10.1016/J.Expneurol.2019.113046 |
0.341 |
|
| 2019 |
Willis CM, Nicaise AM, Menoret A, Ryu JK, Mendiola AS, Jellison ER, Givogri MI, Han DK, Bongarzone ER, Akassoglou K, Vella AT, Crocker SJ. Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31068461 DOI: 10.1073/Pnas.1816911116 |
0.378 |
|
| 2019 |
Yang T, Xu G, Newton PT, Chagin AS, Mkrtchian S, Carlström M, Zhang XM, Harris RA, Cooter M, Berger M, Maddipati KR, Akassoglou K, Terrando N. Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders. British Journal of Anaesthesia. 122: 350-360. PMID 30770053 DOI: 10.1016/J.Bja.2018.10.062 |
0.319 |
|
| 2019 |
Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K. Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model. Neuron. PMID 30737131 DOI: 10.1016/J.Neuron.2019.01.014 |
0.313 |
|
| 2018 |
Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, Bedard C, Hanspers K, Bardehle S, Mendiola AS, Davalos D, ... ... Akassoglou K, et al. Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration. Nature Immunology. PMID 30323343 DOI: 10.1038/S41590-018-0232-X |
0.379 |
|
| 2018 |
Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, et al. Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232263 DOI: 10.1073/Pnas.1811411115 |
0.349 |
|
| 2018 |
Pathak A, Stanley EM, Hickman FE, Wallace N, Brewer B, Li D, Gluska S, Perlson E, Fuhrmann S, Akassoglou K, Bronfman F, Casaccia P, Burnette DT, Carter BD. Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150 Deacetylation by Axonal HDAC1. Developmental Cell. 46: 376-387.e7. PMID 30086304 DOI: 10.1016/J.Devcel.2018.07.001 |
0.321 |
|
| 2018 |
Lee NJ, Ha SK, Sati P, Absinta M, Luciano NJ, Lefeuvre JA, Schindler MK, Leibovitch EC, Ryu JK, Petersen MA, Silva AC, Jacobson S, Akassoglou K, Reich DS. Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination. Brain : a Journal of Neurology. PMID 29688408 DOI: 10.1093/Brain/Awy082 |
0.326 |
|
| 2018 |
Petersen MA, Ryu JK, Akassoglou K. Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics. Nature Reviews. Neuroscience. PMID 29618808 DOI: 10.1038/Nrn.2018.13 |
0.405 |
|
| 2018 |
Elahi F, Altendahl M, Filshtein TJ, Casaletto K, Staffaroni AM, Contreras WR, Karydas AM, Cobigo Y, Fletcher E, Singh B, Martinez O, Rosen HJ, Hinman J, Akassoglou K, Glymour M, et al. P2-245: Endothelial-Derived Exosome Biomarkers Suggest Activation Of Innate Immunity In Subclinical Cerebrovascular Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.932 |
0.319 |
|
| 2017 |
Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B. In Vivo Imaging of CNS Injury and Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 10808-10816. PMID 29118209 DOI: 10.1523/Jneurosci.1826-17.2017 |
0.338 |
|
| 2017 |
Petersen MA, Ryu JK, Chang KJ, Etxeberria A, Bardehle S, Mendiola AS, Kamau-Devers W, Fancy SPJ, Thor A, Bushong EA, Baeza-Raja B, Syme CA, Wu MD, Rios Coronado PE, Meyer-Franke A, ... ... Akassoglou K, et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage. Neuron. PMID 29103804 DOI: 10.1016/J.Neuron.2017.10.008 |
0.401 |
|
| 2017 |
Xu T, Stewart KM, Wang X, Liu K, Xie M, Kyu Ryu J, Li K, Ma T, Wang H, Ni L, Zhu S, Cao N, Zhu D, Zhang Y, Akassoglou K, et al. Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism. Nature. PMID 28783731 DOI: 10.1038/Nature23475 |
0.305 |
|
| 2017 |
Merlini M, Akassoglou K. Alzheimer disease makes new blood contacts. Blood. 129: 2462-2463. PMID 28473412 DOI: 10.1182/Blood-2017-03-772087 |
0.313 |
|
| 2017 |
Krabbe G, Minami SS, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC, Sayed F, Merlini M, Ward ME, Perry DC, Lee SE, ... ... Akassoglou K, et al. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28438992 DOI: 10.1073/Pnas.1700477114 |
0.347 |
|
| 2017 |
Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, et al. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. The Journal of Experimental Medicine. PMID 28298456 DOI: 10.1084/Jem.20162011 |
0.331 |
|
| 2017 |
Shaw MA, Gao Z, McElhinney KE, Thornton S, Flick MJ, Lane A, Degen JL, Kyu Ryu J, Akassoglou K, Mullins ES. Plasminogen deficiency delays the onset and protects from demyelination and paralysis in autoimmune neuroinflammatory disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28275164 DOI: 10.1523/Jneurosci.2932-15.2017 |
0.404 |
|
| 2016 |
Mendiola AS, Garza R, Cardona SM, Mythen SA, Lira SA, Akassoglou K, Cardona AE. Fractalkine Signaling Attenuates Perivascular Clustering of Microglia and Fibrinogen Leakage during Systemic Inflammation in Mouse Models of Diabetic Retinopathy. Frontiers in Cellular Neuroscience. 10: 303. PMID 28119571 DOI: 10.3389/Fncel.2016.00303 |
0.325 |
|
| 2015 |
Bardehle S, Rafalski VA, Akassoglou K. Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface. Frontiers in Cellular Neuroscience. 9: 354. PMID 26441525 DOI: 10.3389/Fncel.2015.00354 |
0.395 |
|
| 2015 |
Ryu JK, Petersen MA, Murray SG, Baeten KM, Meyer-Franke A, Chan JP, Vagena E, Bedard C, Machado MR, Coronado PE, Prod'homme T, Charo IF, Lassmann H, Degen JL, Zamvil SS, ... Akassoglou K, et al. Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation. Nature Communications. 6: 8164. PMID 26353940 DOI: 10.1038/Ncomms9164 |
0.392 |
|
| 2015 |
Schachtrup C, Ryu JK, Mammadzada K, Khan AS, Carlton PM, Perez A, Christian F, Le Moan N, Vagena E, Baeza-Raja B, Rafalski V, Chan JP, Nitschke R, Houslay MD, Ellisman MH, ... ... Akassoglou K, et al. Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions. Nature Neuroscience. PMID 26120963 DOI: 10.1038/Nn.4054 |
0.331 |
|
| 2015 |
Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 607-17. PMID 25918343 DOI: 10.1084/Jem.20132378 |
0.351 |
|
| 2015 |
Akassoglou K. Coagulation takes center stage in inflammation. Blood. 125: 419-20. PMID 25593329 DOI: 10.1182/Blood-2014-11-609222 |
0.308 |
|
| 2014 |
Terrando N, Yang T, Ryu JK, Newton PT, Monaco C, Feldmann M, Ma D, Akassoglou K, Maze M. Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice. Molecular Medicine (Cambridge, Mass.). 20: 667-75. PMID 25365546 DOI: 10.2119/Molmed.2014.00143 |
0.307 |
|
| 2014 |
Gyoneva S, Davalos D, Biswas D, Swanger SA, Garnier-Amblard E, Loth F, Akassoglou K, Traynelis SF. Systemic inflammation regulates microglial responses to tissue damage in vivo. Glia. 62: 1345-60. PMID 24807189 DOI: 10.1002/Glia.22686 |
0.366 |
|
| 2014 |
Davalos D, Baeten KM, Whitney MA, Mullins ES, Friedman B, Olson ES, Ryu JK, Smirnoff DS, Petersen MA, Bedard C, Degen JL, Tsien RY, Akassoglou K. Early detection of thrombin activity in neuroinflammatory disease. Annals of Neurology. 75: 303-8. PMID 24740641 DOI: 10.1002/Ana.24078 |
0.344 |
|
| 2013 |
Chen W, Guo Y, Walker EJ, Shen F, Jun K, Oh SP, Degos V, Lawton MT, Tihan T, Davalos D, Akassoglou K, Nelson J, Pile-Spellman J, Su H, Young WL. Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 305-10. PMID 23241407 DOI: 10.1161/Atvbaha.112.300485 |
0.307 |
|
| 2013 |
Ryu JK, Baeten KM, Petersen MA, Murray SG, Meyer-Franke A, Davalos D, Bedard C, Prod’homme T, Charo IF, Lassmann H, Degen JL, Zamvil SS, Akassoglou K. 220 Cytokine. 63: 295. DOI: 10.1016/J.Cyto.2013.06.223 |
0.398 |
|
| 2012 |
Davalos D, Ryu JK, Merlini M, Baeten KM, Le Moan N, Petersen MA, Deerinck TJ, Smirnoff DS, Bedard C, Hakozaki H, Gonias Murray S, Ling JB, Lassmann H, Degen JL, Ellisman MH, ... Akassoglou K, et al. Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation. Nature Communications. 3: 1227. PMID 23187627 DOI: 10.1038/Ncomms2230 |
0.335 |
|
| 2012 |
Kwan W, Träger U, Davalos D, Chou A, Bouchard J, Andre R, Miller A, Weiss A, Giorgini F, Cheah C, Möller T, Stella N, Akassoglou K, Tabrizi SJ, Muchowski PJ. Mutant huntingtin impairs immune cell migration in Huntington disease. The Journal of Clinical Investigation. 122: 4737-47. PMID 23160193 DOI: 10.1172/Jci64484 |
0.348 |
|
| 2012 |
Pearn ML, Hu Y, Niesman IR, Patel HH, Drummond JC, Roth DM, Akassoglou K, Patel PM, Head BP. Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology. 116: 352-61. PMID 22198221 DOI: 10.1097/Aln.0B013E318242A48C |
0.305 |
|
| 2012 |
Davalos D, Akassoglou K. Fibrinogen as a key regulator of inflammation in disease. Seminars in Immunopathology. 34: 43-62. PMID 22037947 DOI: 10.1007/S00281-011-0290-8 |
0.395 |
|
| 2011 |
Baeten KM, Akassoglou K. Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke. Developmental Neurobiology. 71: 1018-39. PMID 21780303 DOI: 10.1002/Dneu.20954 |
0.36 |
|
| 2011 |
Schachtrup C, Le Moan N, Passino MA, Akassoglou K. Hepatic stellate cells and astrocytes: Stars of scar formation and tissue repair. Cell Cycle (Georgetown, Tex.). 10: 1764-71. PMID 21555919 DOI: 10.4161/Cc.10.11.15828 |
0.304 |
|
| 2010 |
Schachtrup C, Ryu JK, Helmrick MJ, Vagena E, Galanakis DK, Degen JL, Margolis RU, Akassoglou K. Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-β after vascular damage Journal of Neuroscience. 30: 5843-5854. PMID 20427645 DOI: 10.1523/Jneurosci.0137-10.2010 |
0.342 |
|
| 2009 |
Ryu JK, Davalos D, Akassoglou K. Fibrinogen signal transduction in the nervous system. Journal of Thrombosis and Haemostasis : Jth. 7: 151-4. PMID 19630789 DOI: 10.1111/J.1538-7836.2009.03438.X |
0.437 |
|
| 2009 |
Gaultier A, Wu X, Le Moan N, Takimoto S, Mukandala G, Akassoglou K, Campana WM, Gonias SL. Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis. Journal of Cell Science. 122: 1155-62. PMID 19299462 DOI: 10.1242/Jcs.040717 |
0.363 |
|
| 2008 |
Xu M, Remillard CV, Sachs BD, Makino A, Platoshyn O, Yao W, Dillmann WH, Akassoglou K, Yuan JX. p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1529-38. PMID 18689502 DOI: 10.1152/Ajpheart.00115.2008 |
0.311 |
|
| 2007 |
Adams RA, Schachtrup C, Davalos D, Tsigelny I, Akassoglou K. Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis. Current Medicinal Chemistry. 14: 2925-36. PMID 18045138 DOI: 10.2174/092986707782360015 |
0.391 |
|
| 2007 |
Sachs BD, Akassoglou K. Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors. Biochemical Society Transactions. 35: 1273-7. PMID 17956328 DOI: 10.1042/Bst0351273 |
0.321 |
|
| 2007 |
Schachtrup C, Lu P, Jones LL, Lee JK, Lu J, Sachs BD, Zheng B, Akassoglou K. Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 11814-9. PMID 17606926 DOI: 10.1073/Pnas.0704045104 |
0.361 |
|
| 2007 |
Sachs BD, Baillie GS, McCall JR, Passino MA, Schachtrup C, Wallace DA, Dunlop AJ, MacKenzie KF, Klussmann E, Lynch MJ, Sikorski SL, Nuriel T, Tsigelny I, Zhang J, Houslay MD, ... ... Akassoglou K, et al. p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway. The Journal of Cell Biology. 177: 1119-32. PMID 17576803 DOI: 10.1083/Jcb.200701040 |
0.367 |
|
| 2007 |
Passino MA, Adams RA, Sikorski SL, Akassoglou K. Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR. Science (New York, N.Y.). 315: 1853-6. PMID 17395831 DOI: 10.1126/Science.1137603 |
0.313 |
|
| 2007 |
Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K. The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease Journal of Experimental Medicine. 204: 571-582. PMID 17339406 DOI: 10.1084/Jem.20061931 |
0.397 |
|
| 2007 |
Mullins ES, Kombrinck KW, Flick MJ, Shaw MA, Sun W, Degen SJ, Akassoglou K, Degen JL. Reduction of Prothrombin in Mice Carrying a Conditional Knockout Allele Attenuates the Development of Paralysis Associated with Experimental Encephalitis. Blood. 110: 407-407. DOI: 10.1182/Blood.V110.11.407.407 |
0.425 |
|
| 2006 |
Arthur DB, Akassoglou K, Insel PA. P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation. Biochemical and Biophysical Research Communications. 347: 678-82. PMID 16842754 DOI: 10.1016/J.Bbrc.2006.06.141 |
0.303 |
|
| 2006 |
Arthur DB, Georgi S, Akassoglou K, Insel PA. Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3798-804. PMID 16597733 DOI: 10.1523/Jneurosci.5338-05.2006 |
0.329 |
|
| 2006 |
Sachs B, Passino M, Sikorski S, Chao M, Akassoglou K. ID: 248 p75 Neurotrophin Receptor Regulates Fibrinolysis via a cAMP/PKA Pathway Journal of Thrombosis and Haemostasis. 4: 142-142. DOI: 10.1111/J.1538-7836.2006.00248.X |
0.3 |
|
| 2006 |
Adams R, Bauer J, Sikorski S, Nuriel T, Flick M, Lassmann H, Degen J, Akassoglou K. ID: 071 Fibrin/Mac-1 interactions induce microglia activation and regulate relapsing paralysis in central nervous system autoimmune disease Journal of Thrombosis and Haemostasis. 4: 133-133. DOI: 10.1111/J.1538-7836.2006.00071.X |
0.369 |
|
| 2005 |
Arthur DB, Akassoglou K, Insel PA. P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 19138-43. PMID 16365320 DOI: 10.1073/Pnas.0505913102 |
0.338 |
|
| 2005 |
Akassoglou K. Nerve growth factor-independent neuronal survival: a role for NO donors. Molecular Pharmacology. 68: 952-5. PMID 16046659 DOI: 10.1124/Mol.105.017277 |
0.308 |
|
| 2004 |
Adams RA, Passino M, Sachs BD, Nuriel T, Akassoglou K. Fibrin mechanisms and functions in nervous system pathology. Molecular Interventions. 4: 163-76. PMID 15210870 DOI: 10.1124/Mi.4.3.6 |
0.396 |
|
| 2004 |
Akassoglou K, Adams RA, Bauer J, Mercado P, Tseveleki V, Lassmann H, Probert L, Strickland S. Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 6698-703. PMID 15096619 DOI: 10.1073/Pnas.0303859101 |
0.407 |
|
| 2004 |
Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV. Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 101: 5075-80. PMID 15051870 DOI: 10.1073/Pnas.0401030101 |
0.373 |
|
| 2003 |
Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, Probert L. Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 709-14. PMID 12522266 DOI: 10.1073/Pnas.0236046100 |
0.443 |
|
| 2002 |
Akassoglou K, Strickland S. Nervous system pathology: the fibrin perspective. Biological Chemistry. 383: 37-45. PMID 11928820 DOI: 10.1515/Bc.2002.004 |
0.351 |
|
| 2002 |
Akassoglou K, Yu WM, Akpinar P, Strickland S. Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation. Neuron. 33: 861-75. PMID 11906694 DOI: 10.1016/S0896-6273(02)00617-7 |
0.329 |
|
| 2001 |
Probert L, Akassoglou K. Glial expression of tumor necrosis factor in transgenic animals: How do these models reflect the "normal situation"? Glia. 36: 212-219. PMID 11596129 DOI: 10.1002/Glia.1110 |
0.403 |
|
| 2000 |
Probert L, Eugster HP, Akassoglou K, Bauer J, Frei K, Lassmann H, Fontana A. TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain : a Journal of Neurology. 123: 2005-19. PMID 11004118 DOI: 10.1093/Brain/123.10.2005 |
0.405 |
|
| 2000 |
Akassoglou K, Kombrinck KW, Degen JL, Strickland S. Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury Journal of Cell Biology. 149: 1157-1166. PMID 10831618 DOI: 10.1083/Jcb.149.5.1157 |
0.35 |
|
| 2000 |
Akassoglou K, Bauer J, Kassiotis G, Lassmann H, Kollias G, Probert L. Transgenic models of TNF induced demyelination Advances in Experimental Medicine and Biology. 468: 245-259. PMID 10635034 DOI: 10.1007/978-1-4615-4685-6_20 |
0.343 |
|
| 1999 |
Aloe L, Properzi F, Probert L, Akassoglou K, Kassiotis G, Micera A, Fiore M. Learning abilities, NGF and BDNF brain levels in two lines of TNF-α transgenic mice, one characterized by neurological disorders, the other phenotypically normal Brain Research. 840: 125-137. PMID 10517960 DOI: 10.1016/S0006-8993(99)01748-5 |
0.336 |
|
| 1999 |
Kassiotis G, Bauer J, Akassoglou K, Lassmann H, Kollias G, Probert L. A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice European Journal of Immunology. 29: 912-917. PMID 10092095 DOI: 10.1002/(Sici)1521-4141(199903)29:03<912::Aid-Immu912>3.0.Co;2-G |
0.401 |
|
| 1998 |
Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G, Probert L. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy American Journal of Pathology. 153: 801-813. PMID 9736029 DOI: 10.1016/S0002-9440(10)65622-2 |
0.426 |
|
| 1998 |
Akassoglou K, Bauer J, Kassiotis G, Lassmann H, Kollias G, Probert L. Local TNF ligand/receptor signaling induces MS-type plaques in the CNS of transgenic mice Journal of Neuroimmunology. 90: 46. DOI: 10.1016/S0165-5728(98)91454-0 |
0.348 |
|
| 1998 |
Probert L, Akassoglou K, Kassiotis G, Bauer J, Lassmann H, Kozak Yd. The TNF/TNF receptor system in CNS Disease: Studies in transgenic and mutant mice Journal of Neuroimmunology. 90: 9. DOI: 10.1016/S0165-5728(98)91247-4 |
0.37 |
|
| 1997 |
Probert L, Akassoglou K, Kassiotis G, Pasparakis M, Alexopoulou L, Kollias G. TNF-α transgenic and knockout models of CNS inflammation and degeneration Journal of Neuroimmunology. 72: 137-141. PMID 9042105 DOI: 10.1016/S0165-5728(96)00184-1 |
0.364 |
|
| 1997 |
Kassiotis G, Akassoglou K, Kollias G, Probert L. TNF-triggered CNS inflammation, demyelination and T cell autoreactivity in transgenic mice: A role for mature lymphocytes in disease modulation but not disease initiation Immunology Letters. 56: 219. DOI: 10.1016/S0165-2478(97)85875-0 |
0.385 |
|
| 1996 |
Fiore M, Probert L, Kollias G, Akassoglou K, Alleva E, Aloe L. Neurobehavioral alterations in developing transgenic mice expressing TNF-α in the brain Brain, Behavior, and Immunity. 10: 126-138. PMID 8811936 DOI: 10.1006/Brbi.1996.0013 |
0.335 |
|
| 1996 |
Probert L, Akassoglou K, Alexopoulou L, Douni E, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Kollias G. Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice Journal of Leukocyte Biology. 59: 518-525. PMID 8613699 DOI: 10.1002/Jlb.59.4.518 |
0.408 |
|
| 1995 |
Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G, Kollias G. Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor α Proceedings of the National Academy of Sciences of the United States of America. 92: 11294-11298. PMID 7479982 DOI: 10.1073/Pnas.92.24.11294 |
0.398 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Zhang MD, Barde S, Yang T, Lei B, Eriksson LI, Mathew JP, Andreska T, Akassoglou K, Harkany T, Hökfelt TG, Terrando N. Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels. Proceedings of the National Academy of Sciences of the United States of America. 113: E6686-E6695. PMID 27791037 DOI: 10.1073/Pnas.1614017113 |
0.299 |
|
| 2008 |
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 453: 807-11. PMID 18432192 DOI: 10.1038/Nature06905 |
0.299 |
|
| 2016 |
Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EM, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ, Zlokovic BV. Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium. Frontiers in Neuroscience. 10: 46. PMID 26941593 DOI: 10.3389/Fnins.2016.00046 |
0.297 |
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| 1998 |
Kozak Yd, Thillaye-Goldenberg B, Akassoglou K, Kassiotis G, Keller N, Naud MC, Pasparakis M, Kollias G, Probert L. Regulatory role of TNF in experimental ocular inflammation Journal of Neuroimmunology. 90: 55. DOI: 10.1016/S0165-5728(98)91507-7 |
0.297 |
|
| 2012 |
Baeza-Raja B, Akassoglou K. Glucose homeostasis and p75NTR: the sweet side of neurotrophin receptor signaling. Cell Cycle (Georgetown, Tex.). 11: 3151-2. PMID 22894898 DOI: 10.4161/Cc.21590 |
0.296 |
|
| 2006 |
Passino M, Sikorski S, Akassoglou K. ID: 64 Loss of p75 neurotrophin receptor exacerbates the effects of plasminogen deficiency Journal of Thrombosis and Haemostasis. 4: 132-132. DOI: 10.1111/J.1538-7836.2006.00064.X |
0.295 |
|
| 2008 |
Davalos D, Lee JK, Smith WB, Brinkman B, Ellisman MH, Zheng B, Akassoglou K. Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy. Journal of Neuroscience Methods. 169: 1-7. PMID 18192022 DOI: 10.1016/J.Jneumeth.2007.11.011 |
0.294 |
|
| 2011 |
Le Moan N, Houslay DM, Christian F, Houslay MD, Akassoglou K. Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α. Molecular Cell. 44: 476-90. PMID 22055192 DOI: 10.1016/J.Molcel.2011.08.033 |
0.293 |
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| 2015 |
Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, ... ... Akassoglou K, et al. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Reports. PMID 26748707 DOI: 10.1016/J.Celrep.2015.12.028 |
0.292 |
|
| 2013 |
Baeza-Raja B, Eckel-Mahan K, Zhang L, Vagena E, Tsigelny IF, Sassone-Corsi P, Ptácek LJ, Akassoglou K. p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10221-34. PMID 23785138 DOI: 10.1523/Jneurosci.2757-12.2013 |
0.291 |
|
| 2003 |
Akassoglou K, Akpinar P, Murray S, Strickland S. Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice. Neuroscience Letters. 338: 185-8. PMID 12581827 DOI: 10.1016/S0304-3940(02)01387-3 |
0.289 |
|
| 2001 |
Brodsky S, Chen J, Lee A, Akassoglou K, Norman J, Goligorsky MS. Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis American Journal of Physiology - Heart and Circulatory Physiology. 281: H1784-H1792. PMID 11557572 DOI: 10.1152/Ajpheart.2001.281.4.H1784 |
0.288 |
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| 2010 |
Drew PJ, Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai PS, Kleinfeld D. Chronic optical access through a polished and reinforced thinned skull. Nature Methods. 7: 981-4. PMID 20966916 DOI: 10.1038/Nmeth.1530 |
0.285 |
|
| 1997 |
Akassoglou K, Probert L, Kontogeorgos G, Kollias G. Astrocyte-Specific but Not Neuron-Specific Transmembrane TNF Triggers Inflammation and Degeneration in the Central Nervous System of Transgenic Mice Journal of Immunology. 158: 438-445. |
0.284 |
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| 2020 |
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, ... ... Akassoglou K, et al. Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. Nature Immunology. PMID 32284594 DOI: 10.1038/S41590-020-0654-0 |
0.282 |
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| 1995 |
Douni E, Akassoglou K, Alexopoulou L, Georgopoulos S, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Probert L, Kollias G. Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis Journal of Inflammation. 47: 27-38. PMID 8913927 |
0.282 |
|
| 2016 |
Bardehle S, Rafalski V, Akassoglou K. Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation. Nature Immunology. 18: 7-8. PMID 27984564 DOI: 10.1038/Ni.3633 |
0.281 |
|
| 2019 |
Mucke L, Akassoglou K, Das M, Gan L, Ho K, Merlini M, Orr A, Rafalski VA, Ryu JK, Sayed F, Seeley WW, Yu G. ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P188. DOI: 10.1016/J.Jalz.2019.06.4393 |
0.28 |
|
| 2011 |
Terrando N, Eriksson LI, Ryu JK, Yang T, Monaco C, Feldmann M, Jonsson Fagerlund M, Charo IF, Akassoglou K, Maze M. Resolving postoperative neuroinflammation and cognitive decline. Annals of Neurology. 70: 986-95. PMID 22190370 DOI: 10.1002/Ana.22664 |
0.278 |
|
| 2020 |
Akassoglou K. The immunology of blood: connecting the dots at the neurovascular interface. Nature Immunology. 21: 710-712. PMID 32577008 DOI: 10.1038/S41590-020-0671-Z |
0.277 |
|
| 2018 |
Rafalski VA, Merlini M, Akassoglou K. Pericytes: The Brain's Very First Responders? Neuron. 100: 11-13. PMID 30308164 DOI: 10.1016/J.Neuron.2018.09.033 |
0.273 |
|
| 2012 |
Davalos D, Akassoglou K. In vivo imaging of the mouse spinal cord using two-photon microscopy. Journal of Visualized Experiments : Jove. e2760. PMID 22258623 DOI: 10.3791/2760 |
0.272 |
|
| 2008 |
Xu M, Platoshyn O, Makino A, Dillmann WH, Akassoglou K, Remillard CV, Yuan JX. Characterization of agonist-induced vasoconstriction in mouse pulmonary artery. American Journal of Physiology. Heart and Circulatory Physiology. 294: H220-8. PMID 17982012 DOI: 10.1152/Ajpheart.00968.2007 |
0.267 |
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| 2023 |
Mendiola AS, Yan Z, Dixit K, Johnson JR, Bouhaddou M, Meyer-Franke A, Shin MG, Yong Y, Agrawal A, MacDonald E, Muthukumar G, Pearce C, Arun N, Cabriga B, Meza-Acevedo R, ... ... Akassoglou K, et al. Defining blood-induced microglia functions in neurodegeneration through multiomic profiling. Nature Immunology. PMID 37291385 DOI: 10.1038/s41590-023-01522-0 |
0.267 |
|
| 2019 |
Dean T, Rafalski V, Oliveros D, Rios-Coronado P, Ryu J, Akassoglou K. 778 Critical Care Medicine. 47: 368. DOI: 10.1097/01.Ccm.0000551527.06852.77 |
0.264 |
|
| 2013 |
Gut P, Baeza-Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, Akassoglou K, Verdin E, Hirschey MD, Stainier DY. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature Chemical Biology. 9: 97-104. PMID 23201900 DOI: 10.1038/Nchembio.1136 |
0.259 |
|
| 2012 |
Le Moan N, Baeza-Raja B, Akassoglou K. p75 (NTR) and hypoxia: a breath of fresh air in neurotrophin receptor signaling. Cell Cycle (Georgetown, Tex.). 11: 829-30. PMID 22333586 DOI: 10.4161/Cc.11.5.19436 |
0.255 |
|
| 2006 |
Schachtrup C, Lu P, Jones L, Tuszynski M, Akassoglou K. ID: 075 Fibrin deposition and axonal damage in spinal cord injury Journal of Thrombosis and Haemostasis. 4: 134-134. DOI: 10.1111/J.1538-7836.2006.00075.X |
0.254 |
|
| 2013 |
Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (New York, N.Y.). 339: 211-4. PMID 23223453 DOI: 10.1126/Science.1227166 |
0.251 |
|
| 2012 |
Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5838-43. PMID 22460790 DOI: 10.1073/Pnas.1103638109 |
0.25 |
|
| 2009 |
Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. Acute vascular disruption and aquaporin 4 loss after stroke. Stroke; a Journal of Cerebral Circulation. 40: 2182-90. PMID 19372455 DOI: 10.1161/Strokeaha.108.523720 |
0.244 |
|
| 2012 |
Merlini M, Davalos D, Akassoglou K. In vivo imaging of the neurovascular unit in CNS disease. Intravital. 1: 87-94. PMID 25197615 DOI: 10.4161/intv.22214 |
0.239 |
|
| 2021 |
Petersen MA, Tognatta R, Meyer-Franke A, Bushong EA, Mendiola AS, Yan Z, Muthusamy A, Merlini M, Meza-Acevedo R, Cabriga B, Zhou Y, Thomas R, Ryu JK, Lassmann H, Ellisman MH, ... Akassoglou K, et al. BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis. Brain : a Journal of Neurology. PMID 34426831 DOI: 10.1093/brain/awab106 |
0.238 |
|
| 2019 |
Akassoglou K, Tognatta R, Petersen M. Neurovascular interactions: Mechanisms, imaging, and therapeutics Ibro Reports. 6. DOI: 10.1016/J.Ibror.2019.07.097 |
0.236 |
|
| 2008 |
Davalos D, Akassoglou K. Imaging microglia in the central nervous system: Past, present and future Central Nervous System Diseases and Inflammation. 45-57. DOI: 10.1007/978-0-387-73894-9_4 |
0.224 |
|
| 2020 |
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, ... ... Akassoglou K, et al. Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. Nature Immunology. PMID 32661365 DOI: 10.1038/S41590-020-0754-X |
0.224 |
|
| 2018 |
Waubant E, Amezcua L, Sicotte N, Hellwig K, Krupp L, Weinstock-Guttman B, Yeh A, Lucas RM, Longbrake EE, Yadav V, Rensel M, Mar S, Hersh C, Block V, Zipp F, ... ... Akassoglou K, et al. Gender Inequities in the Multiple Sclerosis Community: A Call for Action Annals of Neurology. 84: 958-959. PMID 30387521 DOI: 10.1002/Ana.25359 |
0.223 |
|
| 2023 |
Hashemi E, Srivastava IN, Aguirre A, Yoseph ET, Kaushal E, Awani A, Ryu JK, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, et al. A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 37986739 DOI: 10.1101/2023.11.07.564025 |
0.222 |
|
| 2020 |
Akassoglou K. Author Correction: The immunology of blood: connecting the dots at the neurovascular interface. Nature Immunology. PMID 32636513 DOI: 10.1038/S41590-020-0752-Z |
0.212 |
|
| 2015 |
Le Moan N, Baeten KM, Rafalski VA, Ryu JK, Rios Coronado PE, Bedard C, Syme C, Davalos D, Akassoglou K. Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease(,.) Eneuro. 2. PMID 26213713 DOI: 10.1523/ENEURO.0050-14.2015 |
0.21 |
|
| 2021 |
Tognatta R, Merlini M, Yan Z, Schuck R, Davalos D, Akassoglou K. two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain. Star Protocols. 2: 100638. PMID 34258598 DOI: 10.1016/j.xpro.2021.100638 |
0.208 |
|
| 2022 |
Terrando N, Akassoglou K. Breaking barriers in postoperative delirium. British Journal of Anaesthesia. PMID 35718561 DOI: 10.1016/j.bja.2022.05.004 |
0.208 |
|
| 2021 |
Mendiola AS, Tognatta R, Yan Z, Akassoglou K. ApoE and immunity in Alzheimer's disease and related tauopathies: Low-density lipoprotein receptor to the rescue. Neuron. 109: 2363-2365. PMID 34352209 DOI: 10.1016/j.neuron.2021.07.013 |
0.207 |
|
| 2021 |
Malik SC, Sozmen EG, Baeza-Raja B, Le Moan N, Akassoglou K, Schachtrup C. In vivo functions of p75: challenges and opportunities for an emerging therapeutic target. Trends in Pharmacological Sciences. PMID 34334250 DOI: 10.1016/j.tips.2021.06.006 |
0.204 |
|
| 2020 |
Merlini M, Rafalski VA, Ma K, Kim KY, Bushong EA, Rios Coronado PE, Yan Z, Mendiola AS, Sozmen EG, Ryu JK, Haberl MG, Madany M, Sampson DN, Petersen MA, Bardehle S, ... ... Akassoglou K, et al. Microglial G-dependent dynamics regulate brain network hyperexcitability. Nature Neuroscience. PMID 33318667 DOI: 10.1038/s41593-020-00756-7 |
0.2 |
|
| 2024 |
Dean T, Mendiola AS, Yan Z, Meza-Acevedo R, Cabriga B, Akassoglou K, Ryu JK. Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation. Journal of Neuroinflammation. 21: 94. PMID 38622640 DOI: 10.1186/s12974-024-03092-w |
0.196 |
|
| 2022 |
Merlini M, Sozmen EG, Subramanian KS, Nana AL, Seeley WW, Akassoglou K. Three-Dimensional Imaging of Fibrinogen and Neurovascular Alterations in Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 2561: 87-101. PMID 36399266 DOI: 10.1007/978-1-0716-2655-9_5 |
0.189 |
|
| 2021 |
Chan JP, Merlini M, Gao HX, Mendiola AS, Akassoglou K, Rubenstein JL, Ryu JK. Blood Coagulation Factor Fibrinogen in Tumor Pathogenesis of Central Nervous System B-Cell Lymphoma. The American Journal of Pathology. 191: 575-583. PMID 33608067 DOI: 10.1016/j.ajpath.2020.12.010 |
0.188 |
|
| 2021 |
Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, ... ... Akassoglou K, et al. SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. Biorxiv : the Preprint Server For Biology. PMID 34671772 DOI: 10.1101/2021.10.12.464152 |
0.186 |
|
| 2013 |
Cardona AE, Ransohoff RM, Akassoglou K. Microglia Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 803-817. DOI: 10.1016/B978-0-12-397265-1.00085-X |
0.17 |
|
| 2023 |
Browning JL, Bhawan J, Tseng A, Crossland N, Bujor AM, Akassoglou K, Assassi S, Skaug B, Ho J. Extensive and Persistent Extravascular Dermal Fibrin Deposition Characterizes Systemic Sclerosis. Biorxiv : the Preprint Server For Biology. PMID 36711912 DOI: 10.1101/2023.01.16.523256 |
0.163 |
|
| 2006 |
Passino M, Sikorski S, Akassoglou K. 84 P75 neurotrophin receptor promotes liver regeneration via regulation of hepatic stellate cell differentiation Journal of Hepatology. 44: S37-S38. DOI: 10.1016/S0168-8278(06)80085-1 |
0.148 |
|
| 2021 |
Sozmen EG, Akassoglou K. Coagulation and immunity: Caught in the fibrin web. Immunity. 54: 2439-2441. PMID 34758333 DOI: 10.1016/j.immuni.2021.10.016 |
0.14 |
|
| 2022 |
Bernier RA, Banks SJ, Panizzon MS, Andrews MJ, Jacobs EG, Galasko DR, Shepherd AL, Akassoglou K, Sundermann EE. The neuroinflammatory marker sTNFR2 relates to worse cognition and tau in women across the Alzheimer's disease spectrum. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12284. PMID 35386474 DOI: 10.1002/dad2.12284 |
0.108 |
|
| 2015 |
Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 973. PMID 25987725 DOI: 10.1084/jem.2013237805062015c |
0.091 |
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