Huaxi Xu, Ph.D. - Publications

Affiliations: 
2003- SBP Medical Discovery Institute 

186/493 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang D, Zhang W, Ming C, Gao X, Yuan H, Lin X, Mao X, Wang C, Guo X, Du Y, Shao L, Yang R, Lin Z, Wu X, Huang TY, ... ... Xu H, et al. P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy. Neuron. PMID 38513667 DOI: 10.1016/j.neuron.2024.02.017  0.722
2023 Cui Q, Liang S, Li H, Guo Y, Lv J, Wang X, Qin P, Xu H, Huang TY, Lu Y, Tian Q, Zhang T. SNX17 Mediates Dendritic Spine Maturation via p140Cap. Molecular Neurobiology. PMID 37704928 DOI: 10.1007/s12035-023-03620-4  0.656
2023 Lee CYD, De La Rocha AJ, Inouye K, Langfelder P, Daggett A, Gu X, Jiang LL, Pamonag Z, Vaca RG, Richman J, Kawaguchi R, Gao F, Xu H, Yang XW. BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice. Biorxiv : the Preprint Server For Biology. PMID 37577582 DOI: 10.1101/2023.08.03.551881  0.711
2023 Zhao Y, Zheng Q, Hong Y, Gao Y, Hu J, Lang M, Zhang H, Zhou Y, Luo H, Zhang X, Sun H, Yan XX, Huang TY, Wang YJ, Xu H, et al. β-Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer's disease model mice. Nature Neuroscience. PMID 37264159 DOI: 10.1038/s41593-023-01352-1  0.741
2023 Gao Y, Hong Y, Huang L, Zheng S, Zhang H, Wang S, Yao Y, Zhao Y, Zhu L, Xu Q, Chai X, Zeng Y, Zeng Y, Zheng L, Zhou Y, ... ... Xu H, et al. β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function. Cell. 186: 1026-1038.e20. PMID 36868208 DOI: 10.1016/j.cell.2023.01.021  0.635
2022 Leng L, Yuan Z, Pan R, Su X, Wang H, Xue J, Zhuang K, Gao J, Chen Z, Lin H, Xie W, Li H, Chen Z, Ren K, Zhang X, ... ... Xu H, et al. Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance. Nature Metabolism. PMID 36203054 DOI: 10.1038/s42255-022-00643-4  0.409
2022 Zhao P, Xu Y, Jiang L, Fan X, Li L, Li X, Arase H, Zhao Y, Cao W, Zheng H, Xu H, Tong Q, Zhang N, An Z. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science Translational Medicine. 14: eabq0095. PMID 36070367 DOI: 10.1126/scitranslmed.abq0095  0.708
2022 Zhu B, Liu Y, Hwang S, Archuleta K, Huang H, Campos A, Murad R, Piña-Crespo J, Xu H, Huang TY. Trem2 deletion enhances tau dispersion and pathology through microglia exosomes. Molecular Neurodegeneration. 17: 58. PMID 36056435 DOI: 10.1186/s13024-022-00562-8  0.832
2022 Guo T, Pan X, Jiang G, Zhang D, Qi J, Shao L, Wang Z, Xu H, Zhao Y. Downregulating PTBP1 fails to convert astrocytes into hippocampal neurons and to alleviate symptoms in Alzheimer's mouse models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35944999 DOI: 10.1523/JNEUROSCI.1060-22.2022  0.375
2022 Wang C, Zhang Y, Zhao D, Huo Y, Xie J, Zhang X, Luo H, Xu H, Zhang YW. Phenazopyridine promotes RPS23RG1/Rps23rg1 transcription and ameliorates Alzheimer-associated phenotypes in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35821069 DOI: 10.1038/s41386-022-01373-7  0.366
2022 Zhao P, Xu Y, Jiang LL, Fan X, Ku Z, Li L, Liu X, Deng M, Arase H, Zhu JJ, Huang TY, Zhao Y, Zhang C, Xu H, Tong Q, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Molecular Neurodegeneration. 17: 44. PMID 35717259 DOI: 10.1186/s13024-022-00550-y  0.77
2022 Shi D, Xie S, Li A, Wang Q, Guo H, Han Y, Xu H, Gan WB, Zhang L, Guo T. APOE-ε4 modulates the association among plasma Aβ/Aβ, vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adults. Translational Psychiatry. 12: 128. PMID 35351867 DOI: 10.1038/s41398-022-01899-w  0.309
2022 Zheng Q, Song B, Li G, Cai F, Wu M, Zhao Y, Jiang L, Guo T, Shen M, Hou H, Zhou Y, Zhao Y, Di A, Zhang L, Zeng F, ... ... Xu H, et al. USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of Clinical Investigation. 132. PMID 35229730 DOI: 10.1172/JCI152170  0.808
2021 Sheng X, Yao Y, Huang R, Xu Y, Zhu Y, Chen L, Zhang L, Wang W, Zhuo R, Can D, Chang CF, Zhang YW, Xu H, Bu G, Zhong L, et al. Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology. Journal of Neuroinflammation. 18: 286. PMID 34893068 DOI: 10.1186/s12974-021-02340-7  0.431
2021 Hu B, Duan S, Wang Z, Li X, Zhou Y, Zhang X, Zhang YW, Xu H, Zheng H. Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders. Frontiers in Aging Neuroscience. 13: 789834. PMID 34867307 DOI: 10.3389/fnagi.2021.789834  0.348
2021 Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang LL, Huang T, Luo W, Xu H, Nairn AC, Flajolet M, Ip NY, Li YM, et al. GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218. PMID 34156424 DOI: 10.1084/jem.20202446  0.832
2021 Cheng B, Li X, Dai K, Duan S, Rong Z, Chen Y, Lü L, Liu Z, Huang X, Xu H, Zhang YW, Zheng H. Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival. Frontiers in Immunology. 12: 633796. PMID 33841415 DOI: 10.3389/fimmu.2021.633796  0.309
2021 Zheng Q, Li G, Wang S, Zhou Y, Liu K, Gao Y, Zhou Y, Zheng L, Zhu L, Deng Q, Wu M, Di A, Zhang L, Zhao Y, Zhang H, ... ... Xu H, et al. Trisomy 21-induced dysregulation of microglial homeostasis in Alzheimer's brains is mediated by USP25. Science Advances. 7. PMID 33523861 DOI: 10.1126/sciadv.abe1340  0.363
2020 Meng J, Han L, Zheng N, Xu H, Liu Z, Zhang X, Luo H, Can D, Sun H, Xu H, Zhang YW. TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer's Disease. Frontiers in Cell and Developmental Biology. 8: 596030. PMID 33195275 DOI: 10.3389/fcell.2020.596030  0.446
2020 Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, ... Xu H, et al. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217. PMID 32941599 DOI: 10.1084/Jem.20200474  0.817
2020 Zhao D, Zhou Y, Huo Y, Meng J, Xiao X, Han L, Zhang X, Luo H, Can D, Sun H, Huang TY, Wang X, Zhang J, Liu FR, Xu H, et al. RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation. Cell Death and Differentiation. PMID 32908202 DOI: 10.1038/S41418-020-00620-Y  0.699
2020 Liu Z, Ning J, Zheng X, Meng J, Han L, Zheng H, Zhong L, Chen XF, Zhang X, Luo H, Can D, Xu H, Zhang YW. TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities. Cell Death & Disease. 11: 678. PMID 32826884 DOI: 10.1038/S41419-020-02874-3  0.382
2020 Guo T, Zhang D, Zeng Y, Huang TY, Xu H, Zhao Y. Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease. Molecular Neurodegeneration. 15: 40. PMID 32677986 DOI: 10.1186/S13024-020-00391-7  0.752
2020 Stupack J, Xiong XP, Jiang LL, Zhang T, Zhou L, Campos A, Ranscht B, Mobley W, Pasquale EB, Xu H, Huang TY. Soluble SORLA enhances neurite outgrowth and regeneration through activation of the EGF Receptor/ERK signaling axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32601248 DOI: 10.1523/Jneurosci.0723-20.2020  0.76
2020 Zhang Z, Chen C, Jia S, Cao X, Liu M, Tian J, Hoffmann PR, Xu H, Ni J, Song G. Selenium restores synaptic deficits by modulating NMDA receptors and selenoprotein K in an Alzheimer's disease model. Antioxidants & Redox Signaling. PMID 32475153 DOI: 10.1089/ars.2019.7990  0.342
2020 Zhu Q, Jiang J, Gendron TF, McAlonis-Downes M, Jiang L, Taylor A, Diaz Garcia S, Ghosh Dastidar S, Rodriguez MJ, King P, Zhang Y, La Spada AR, Xu H, Petrucelli L, Ravits J, et al. Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72. Nature Neuroscience. PMID 32284607 DOI: 10.1038/S41593-020-0619-5  0.653
2020 Zhang F, Gannon M, Chen Y, Yan S, Zhang S, Feng W, Tao J, Sha B, Liu Z, Saito T, Saido T, Keene CD, Jiao K, Roberson ED, Xu H, et al. β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade. Science Translational Medicine. 12. PMID 31941827 DOI: 10.1126/Scitranslmed.Aay6931  0.463
2020 Liu FR, Yang LY, Zheng HF, Zhou Y, Chen BB, Xu H, Zhang YW, Shen DY. Plasma levels of Interleukin 18 but not amyloid-β or Tau are elevated in female depressive patients. Comprehensive Psychiatry. 97: 152159. PMID 31931428 DOI: 10.1016/J.Comppsych.2020.152159  0.421
2019 Zhou J, Chow HM, Liu Y, Wu D, Shi M, Li J, Wen L, Gao Y, Chen G, Zhuang K, Lin H, Zhang G, Xie W, Li H, Leng L, ... ... Xu H, et al. Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover. Biological Psychiatry. PMID 31955914 DOI: 10.1016/J.Biopsych.2019.11.013  0.696
2019 Zeng F, Ma X, Zhu L, Xu Q, Zeng Y, Gao Y, Li G, Guo T, Zhang H, Tang X, Wang Z, Ye Z, Zheng L, Zhang H, Zheng Q, ... ... Xu H, et al. The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability. Plos Biology. 17: e3000525. PMID 31841517 DOI: 10.1371/Journal.Pbio.3000525  0.679
2019 Zhang C, Tan Z, Xie Y, Zhao Y, Huang TY, Lu Z, Luo H, Can D, Xu H, Zhang YW, Zhang X. Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway. Frontiers in Aging Neuroscience. 11: 243. PMID 31551758 DOI: 10.3389/Fnagi.2019.00243  0.672
2019 Xie Y, Niu M, Ji C, Huang TY, Zhang C, Tian Y, Shi Z, Wang C, Zhao Y, Luo H, Can D, Xu H, Zhang YW, Zhang X. SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse. Frontiers in Cellular Neuroscience. 13: 410. PMID 31551717 DOI: 10.3389/Fncel.2019.00410  0.764
2019 Huang TY, Xu H. Bringing Order out of Chaos: Establishing an Epistatic Relationship between CD33 and TREM2. Neuron. 103: 747-749. PMID 31487521 DOI: 10.1016/J.Neuron.2019.08.019  0.669
2019 Zhao S, Li Z, Zhang M, Zhang L, Zheng H, Ning J, Wang Y, Wang F, Zhang X, Gan H, Wang Y, Zhang X, Luo H, Bu G, Xu H, et al. A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II. Experimental & Molecular Medicine. 51: 84. PMID 31337748 DOI: 10.1038/S12276-019-0277-4  0.342
2019 Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Xu H, et al. Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 2923. PMID 31266955 DOI: 10.1038/S41467-019-10950-2  0.322
2019 Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Huang TY, ... Xu H, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130. PMID 31112137 DOI: 10.1172/Jci127695  0.769
2019 Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Xu H, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 1365. PMID 30911003 DOI: 10.1038/S41467-019-09118-9  0.566
2018 Zeng Y, Wang N, Guo T, Zheng Q, Wang S, Wu S, Li X, Wu J, Chen Z, Xu H, Wang X, Lin B. Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation. Frontiers in Neurology. 9: 1059. PMID 30619032 DOI: 10.3389/Fneur.2018.01059  0.303
2018 Cockerill I, Oliver JA, Xu H, Fu BM, Zhu D. Blood-Brain Barrier Integrity and Clearance of Amyloid-β from the BBB. Advances in Experimental Medicine and Biology. 1097: 261-278. PMID 30315550 DOI: 10.1007/978-3-319-96445-4_14  0.41
2018 Zhao D, Meng J, Zhao Y, Huo Y, Liu Y, Zheng N, Zhang M, Gao Y, Chen Z, Sun H, Wang X, Jing C, Zhang T, Zhang X, Luo H, ... ... Xu H, et al. RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits. Biological Psychiatry. PMID 30292394 DOI: 10.1016/J.Biopsych.2018.08.009  0.714
2018 Leng L, Zhuang K, Liu Z, Huang C, Gao Y, Chen G, Lin H, Hu Y, Wu D, Shi M, Xie W, Sun H, Shao Z, Li H, Zhang K, ... ... Xu H, et al. Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation. Neuron. PMID 30220511 DOI: 10.1016/J.Neuron.2018.08.031  0.648
2018 Simandi Z, Pajer K, Karolyi K, Sieler T, Jiang LL, Kolostyak Z, Sari Z, Fekecs Z, Pap A, Patsalos A, Contreras GA, Reho B, Papp Z, Guo X, Horvath A, ... ... Xu H, et al. Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30054395 DOI: 10.1523/Jneurosci.3389-17.2018  0.622
2018 Zhuang K, Huang C, Leng L, Zheng H, Gao Y, Chen G, Ji Z, Sun H, Hu Y, Wu D, Shi M, Li H, Zhao Y, Zhang Y, Xue M, ... ... Xu H, et al. Neuron-Specific Menin Deletion Leads to Synaptic Dysfunction and Cognitive Impairment by Modulating p35 Expression. Cell Reports. 24: 701-712. PMID 30021166 DOI: 10.1016/J.Celrep.2018.06.055  0.662
2018 Pan G, Chen Z, Zheng H, Zhang Y, Xu H, Bu G, Zheng H, Li Y. Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model. Frontiers in Neural Circuits. 12: 48. PMID 30008664 DOI: 10.3389/Fncir.2018.00048  0.312
2018 Li X, Cui XX, Chen YJ, Wu TT, Xu H, Yin H, Wu YC. Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases and : Regulation of Redox Biology and Mitochondrial Function. Frontiers in Aging Neuroscience. 10: 121. PMID 29755339 DOI: 10.3389/Fnagi.2018.00121  0.323
2018 Du Y, Zhao Y, Li C, Zheng Q, Tian J, Li Z, Huang TY, Zhang W, Xu H. Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes. The Journal of Experimental Medicine. PMID 29739836 DOI: 10.1084/Jem.20171193  0.776
2018 Zhang H, Huang T, Hong Y, Yang W, Zhang X, Luo H, Xu H, Wang X. The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases. Frontiers in Aging Neuroscience. 10: 79. PMID 29632483 DOI: 10.3389/Fnagi.2018.00079  0.754
2018 Zhong L, Wang Z, Wang D, Wang Z, Martens YA, Wu L, Xu Y, Wang K, Li J, Huang R, Can D, Xu H, Bu G, Chen XF. Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2). Molecular Neurodegeneration. 13: 15. PMID 29587871 DOI: 10.1186/S13024-018-0247-7  0.496
2018 Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5. PMID 29518357 DOI: 10.1016/J.Neuron.2018.02.002  0.737
2018 Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y, Sun Y, Zhu B, Piña-Crespo JC, Zhang M, Zhang N, Chen X, Bu G, An Z, Huang TY, ... Xu H, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 97: 1023-1031.e7. PMID 29518356 DOI: 10.1016/J.Neuron.2018.01.031  0.836
2018 Zhu D, Su Y, Fu B, Xu H. Magnesium Reduces Blood-Brain Barrier Permeability and Regulates Amyloid-β Transcytosis. Molecular Neurobiology. PMID 29383689 DOI: 10.1007/S12035-018-0896-0  0.461
2017 Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Intracellular trafficking of TREM2 is regulated by presenilin 1. Experimental & Molecular Medicine. 49: e405. PMID 29611543 DOI: 10.1038/Emm.2017.200  0.831
2017 Wu XL, Piña-Crespo J, Zhang YW, Chen XC, Xu HX. Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease. Chinese Medical Journal. 130: 2978-2990. PMID 29237931 DOI: 10.4103/0366-6999.220313  0.773
2017 Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity. Nature Communications. 8: 1472. PMID 29133892 DOI: 10.1038/S41467-017-01799-4  0.832
2017 Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, ... ... Xu H, et al. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nature Communications. 8: 1488. PMID 29133852 DOI: 10.1038/S41467-017-01563-8  0.353
2017 Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration. The Journal of Experimental Medicine. PMID 29114064 DOI: 10.1084/Jem.20171413  0.841
2017 Li Y, Chen Z, Gao Y, Pan G, Zheng H, Zhang Y, Xu H, Bu G, Zheng H. Synaptic adhesion molecule Pcdh-γC5 mediates synaptic dysfunction in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28842416 DOI: 10.1523/Jneurosci.1051-17.2017  0.439
2017 Zhong L, Zhang ZL, Li X, Liao C, Mou P, Wang T, Wang Z, Wang Z, Wei M, Xu H, Bu G, Chen XF. TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway. Frontiers in Aging Neuroscience. 9: 204. PMID 28680398 DOI: 10.3389/Fnagi.2017.00204  0.417
2017 Zhong L, Chen XF, Wang T, Wang Z, Liao C, Wang Z, Huang R, Wang D, Li X, Wu L, Jia L, Zheng H, Painter M, Atagi Y, Liu CC, ... ... Xu H, et al. Soluble TREM2 induces inflammatory responses and enhances microglial survival. The Journal of Experimental Medicine. PMID 28209725 DOI: 10.1084/Jem.20160844  0.448
2017 Zheng H, Jia L, Liu CC, Li Zhong ZR, Yang L, Chen XF, Fryer JD, Wang X, Zhang YW, Xu H, Bu G. TREM2 promotes microglial survival by activating Wnt/β-catenin pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28077724 DOI: 10.1523/Jneurosci.2459-16.2017  0.48
2016 Zheng Q, Huang T, Zhang L, Zhou Y, Luo H, Xu H, Wang X. Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases. Frontiers in Aging Neuroscience. 8: 303. PMID 28018215 DOI: 10.3389/Fnagi.2016.00303  0.693
2016 Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H. SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 12586-12597. PMID 27974614 DOI: 10.1523/Jneurosci.1620-16.2016  0.683
2016 Yang L, Liu CC, Zheng H, Kanekiyo T, Atagi Y, Jia L, Wang D, N'songo A, Can D, Xu H, Chen XF, Bu G. LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways. Journal of Neuroinflammation. 13: 304. PMID 27931217 DOI: 10.1186/S12974-016-0772-7  0.475
2016 Huang TY, Zhao Y, Li X, Wang X, Tseng IC, Thompson R, Tu S, Willnow TE, Zhang YW, Xu H. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7996-8011. PMID 27466343 DOI: 10.1523/Jneurosci.0206-16.2016  0.784
2016 Wang C, Niu M, Zhou Z, Zheng X, Zhang L, Tian Y, Yu X, Bu G, Xu H, Ma Q, Zhang YW. VPS35 regulates cell surface recycling and signaling of dopamine receptor D1. Neurobiology of Aging. 46: 22-31. PMID 27460146 DOI: 10.1016/J.Neurobiolaging.2016.05.016  0.337
2016 Zheng Q, Zheng X, Zhang L, Luo H, Qian L, Fu X, Liu Y, Gao Y, Niu M, Meng J, Zhang M, Bu G, Xu H, Zhang YW. The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death. Molecular Neurobiology. PMID 27324899 DOI: 10.1007/S12035-016-9997-9  0.365
2016 Zheng H, Liu CC, Atagi Y, Chen XF, Jia L, Yang L, He W, Zhang X, Kang SS, Rosenberry TL, Fryer JD, Zhang YW, Xu H, Bu G. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation. Neurobiology of Aging. 42: 132-41. PMID 27143430 DOI: 10.1016/J.Neurobiolaging.2016.03.004  0.514
2016 Zhang X, Hu J, Zhong L, Wang N, Yang L, Liu CC, Li H, Wang X, Zhou Y, Zhang Y, Xu H, Bu G, Zhuang J. Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice. Neuropharmacology. PMID 27114256 DOI: 10.1016/J.Neuropharm.2016.04.032  0.516
2016 Li Y, Sun H, Chen Z, Xu H, Bu G, Zheng H. Implications of GABAergic Neurotransmission in Alzheimer's Disease. Frontiers in Aging Neuroscience. 8: 31. PMID 26941642 DOI: 10.3389/Fnagi.2016.00031  0.542
2016 Barini E, Antico O, Zhao Y, Asta F, Tucci V, Catelani T, Marotta R, Xu H, Gasparini L. Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy. Molecular Neurodegeneration. 11: 16. PMID 26858121 DOI: 10.1186/S13024-016-0082-7  0.433
2016 Zhang C, Shi Z, Zhang L, Zhou Z, Zheng X, Liu G, Bu G, Fraser PE, Xu H, Zhang YW. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. Journal of Cell Science. PMID 26813789 DOI: 10.1242/Jcs.176792  0.307
2016 Yan L, Chen Y, Li W, Huang X, Badie H, Jian F, Huang T, Zhao Y, Cohen SN, Li L, Zhang YW, Luo H, Tu S, Xu H. RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits. Scientific Reports. 6: 18668. PMID 26733416 DOI: 10.1038/Srep18668  0.743
2015 Atagi Y, Liu CC, Painter MM, Chen XF, Verbeeck C, Zheng H, Li X, Rademakers R, Kang SS, Xu H, Younkin S, Das P, Fryer JD, Bu G. Apolipoprotein E is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2). The Journal of Biological Chemistry. PMID 26374899 DOI: 10.1074/Jbc.M115.679043  0.492
2015 Painter MM, Atagi Y, Liu CC, Rademakers R, Xu H, Fryer JD, Bu G. TREM2 in CNS homeostasis and neurodegenerative disease. Molecular Neurodegeneration. 10: 43. PMID 26337043 DOI: 10.1186/S13024-015-0040-9  0.407
2015 Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, ... ... Xu H, et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 87: 963-75. PMID 26335643 DOI: 10.1016/J.Neuron.2015.08.020  0.714
2015 Feng T, Niu M, Ji C, Gao Y, Wen J, Bu G, Xu H, Zhang YW. SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation. Molecular Neurobiology. PMID 26115702 DOI: 10.1007/S12035-015-9306-Z  0.567
2015 Feng Y, Liu T, Dong SY, Guo YJ, Jankovic J, Xu H, Wu YC. Rotenone affects p53 transcriptional activity and apoptosis via targeting SIRT1 and H3K9 acetylation in SH-SY5Y cells. Journal of Neurochemistry. 134: 668-76. PMID 25991017 DOI: 10.1111/Jnc.13172  0.323
2015 Zhong L, Chen XF, Zhang ZL, Wang Z, Shi XZ, Xu K, Zhang YW, Xu H, Bu G. DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response. The Journal of Biological Chemistry. 290: 15866-77. PMID 25957402 DOI: 10.1074/Jbc.M115.645986  0.359
2015 Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice. Molecular Neurodegeneration. 10: 6. PMID 25871773 DOI: 10.1186/S13024-015-0001-3  0.493
2015 Zhou J, Li H, Li X, Zhang G, Niu Y, Yuan Z, Herrup K, Zhang YW, Bu G, Xu H, Zhang J. The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2624-35. PMID 25673854 DOI: 10.1523/Jneurosci.3051-14.2015  0.392
2015 Hu J, Lin T, Gao Y, Xu J, Jiang C, Wang G, Bu G, Xu H, Chen H, Zhang YW. The resveratrol trimer miyabenol C inhibits β-secretase activity and β-amyloid generation. Plos One. 10: e0115973. PMID 25629409 DOI: 10.1371/Journal.Pone.0115973  0.475
2015 Hou P, Liu G, Zhao Y, Shi Z, Zheng Q, Bu G, Xu H, Zhang YW. The role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation. Neurobiology of Aging. 36: 1310-5. PMID 25557959 DOI: 10.1016/J.Neurobiolaging.2014.12.005  0.497
2015 Shukla M, Htoo HH, Wintachai P, Hernandez JF, Dubois C, Postina R, Xu H, Checler F, Smith DR, Govitrapong P, Vincent B. Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17. Journal of Pineal Research. 58: 151-65. PMID 25491598 DOI: 10.1111/Jpi.12200  0.485
2014 Zhang X, Li Y, Xu H, Zhang YW. The γ-secretase complex: from structure to function. Frontiers in Cellular Neuroscience. 8: 427. PMID 25565961 DOI: 10.3389/Fncel.2014.00427  0.444
2014 Wang X, Huang T, Zhao Y, Zheng Q, Thompson RC, Bu G, Zhang YW, Hong W, Xu H. Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity. Cell Reports. 9: 1023-33. PMID 25437557 DOI: 10.1016/J.Celrep.2014.09.037  0.771
2014 Tu S, Okamoto S, Lipton SA, Xu H. Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease. Molecular Neurodegeneration. 9: 48. PMID 25394486 DOI: 10.1186/1750-1326-9-48  0.492
2014 Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. Neuron. 84: 63-77. PMID 25242217 DOI: 10.1016/J.Neuron.2014.08.048  0.554
2014 Wang X, Huang T, Bu G, Xu H. Dysregulation of protein trafficking in neurodegeneration. Molecular Neurodegeneration. 9: 31. PMID 25152012 DOI: 10.1186/1750-1326-9-31  0.759
2014 Jiang S, Li Y, Zhang C, Zhao Y, Bu G, Xu H, Zhang YW. M1 muscarinic acetylcholine receptor in Alzheimer's disease. Neuroscience Bulletin. 30: 295-307. PMID 24590577 DOI: 10.1007/S12264-013-1406-Z  0.428
2014 Kanekiyo T, Xu H, Bu G. ApoE and Aβ in Alzheimer's disease: accidental encounters or partners? Neuron. 81: 740-54. PMID 24559670 DOI: 10.1016/J.Neuron.2014.01.045  0.503
2014 Chen Y, Wang B, Liu D, Li JJ, Xue Y, Sakata K, Zhu LQ, Heldt SA, Xu H, Liao FF. Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2464-70. PMID 24523537 DOI: 10.1523/Jneurosci.0151-13.2014  0.447
2014 Jiang S, Li Y, Zhang X, Bu G, Xu H, Zhang YW. Trafficking regulation of proteins in Alzheimer's disease. Molecular Neurodegeneration. 9: 6. PMID 24410826 DOI: 10.1186/1750-1326-9-6  0.531
2013 Sun L, Zhao Y, Zhou K, Freeze HH, Zhang YW, Xu H. Insufficient ER-stress response causes selective mouse cerebellar granule cell degeneration resembling that seen in congenital disorders of glycosylation. Molecular Brain. 6: 52. PMID 24305089 DOI: 10.1186/1756-6606-6-52  0.342
2013 Zhang YW, Chen Y, Liu Y, Zhao Y, Liao F, Xu H. APP regulates NGF receptor trafficking and NGF-mediated neuronal differentiation and survival. Plos One. 8. PMID 24224055 DOI: 10.1371/Journal.Pone.0080571  0.435
2013 Chen XF, Zhang YW, Xu H, Bu G. Transcriptional regulation and its misregulation in Alzheimer's disease. Molecular Brain. 6: 44. PMID 24144318 DOI: 10.1186/1756-6606-6-44  0.499
2013 Nakanishi N, Ryan SD, Zhang X, Khan A, Holland T, Cho EG, Huang X, Liao FF, Xu H, Lipton SA, Tu S. Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14170-83. PMID 23986251 DOI: 10.1523/Jneurosci.4646-10.2013  0.46
2013 Li X, Liu Y, Zheng Q, Yao G, Cheng P, Bu G, Xu H, Zhang YW. Ferritin light chain interacts with PEN-2 and affects γ-secretase activity. Neuroscience Letters. 548: 90-4. PMID 23685131 DOI: 10.1016/J.Neulet.2013.05.018  0.434
2013 Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, ... ... Xu H, et al. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nature Medicine. 19: 473-80. PMID 23524343 DOI: 10.1038/Nm.3117  0.372
2013 Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nature Reviews. Neurology. 9: 106-18. PMID 23296339 DOI: 10.1038/Nrneurol.2012.263  0.446
2013 Wang X, Zhao Y, Zhang X, Zhou Y, Ranscht B, Gage FH, Mobley WC, Zhang Y, Lipton SA, Hong W, Xu H. A novel mechanism underlying pathogenesis of Down syndrome Molecular Neurodegeneration. 8: O23. DOI: 10.1186/1750-1326-8-S1-O23  0.44
2013 Liu CC, Kanekiyo T, Xu H, Bu G. Erratum: Apolipoprotein e and Alzheimer disease: Risk, mechanisms and therapy (Nature Reviews Neurology (2013) 9 (106-118)) Nature Reviews Neurology. 9. DOI: 10.1038/Nrneurol2013.32  0.328
2012 Li J, Kanekiyo T, Shinohara M, Zhang Y, LaDu MJ, Xu H, Bu G. Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms. The Journal of Biological Chemistry. 287: 44593-601. PMID 23132858 DOI: 10.1074/Jbc.M112.420224  0.53
2012 Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, ... Xu H, et al. Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15565-76. PMID 23115192 DOI: 10.1523/Jneurosci.3668-12.2012  0.409
2012 Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, Masliah E, Xu H. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11390-5. PMID 22895721 DOI: 10.1523/Jneurosci.0757-12.2012  0.541
2012 Kwak YD, Wang B, Li JJ, Wang R, Deng Q, Diao S, Chen Y, Xu R, Masliah E, Xu H, Sung JJ, Liao FF. Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10971-81. PMID 22875931 DOI: 10.1523/Jneurosci.1836-12.2012  0.395
2012 Zhang H, Ma Q, Zhang YW, Xu H. Proteolytic processing of Alzheimer's β-amyloid precursor protein. Journal of Neurochemistry. 120: 9-21. PMID 22122372 DOI: 10.1111/J.1471-4159.2011.07519.X  0.551
2012 Huang X, Chen Y, Zhang H, Ma Q, Zhang YW, Xu H. Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway. Neurobiology of Aging. 33: 1007.e9-17. PMID 22056200 DOI: 10.1016/J.Neurobiolaging.2011.10.007  0.497
2012 Zhang Y, Xu H. Identifying an APP-binding protein in neuronal cell death Molecular Neurodegeneration. 7: L22. DOI: 10.1186/1750-1326-7-S1-L22  0.369
2011 Kwak YD, Wang R, Li JJ, Zhang YW, Xu H, Liao FF. Differential regulation of BACE1 expression by oxidative and nitrosative signals. Molecular Neurodegeneration. 6: 17. PMID 21371311 DOI: 10.1186/1750-1326-6-17  0.495
2011 Zhang YW, Thompson R, Zhang H, Xu H. APP processing in Alzheimer's disease. Molecular Brain. 4: 3. PMID 21214928 DOI: 10.1186/1756-6606-4-3  0.545
2010 Kwak YD, Ma T, Diao S, Zhang X, Chen Y, Hsu J, Lipton SA, Masliah E, Xu H, Liao FF. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. Molecular Neurodegeneration. 5: 49. PMID 21067594 DOI: 10.1186/1750-1326-5-49  0.429
2010 Huang X, Chen Y, Li WB, Cohen SN, Liao FF, Li L, Xu H, Zhang YW. The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's β-amyloid level and tau phosphorylation Human Molecular Genetics. 19: 3835-3843. PMID 20650958 DOI: 10.1093/Hmg/Ddq302  0.491
2010 Zhang YW, Xu H. Substrate check of gamma-secretase. Nature Structural & Molecular Biology. 17: 140-1. PMID 20130572 DOI: 10.1038/Nsmb0210-140  0.485
2010 Kwak YD, Wang B, Pan W, Xu H, Jiang X, Liao FF. Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc. The Journal of Biological Chemistry. 285: 9847-57. PMID 20100827 DOI: 10.1074/Jbc.M109.091637  0.384
2010 Bulloj A, Leal MC, Xu H, Castaño EM, Morelli L. Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-β Degrading Protease Journal of Alzheimer's Disease. 19: 79-95. PMID 20061628 DOI: 10.3233/Jad-2010-1206  0.489
2010 Zhang Y, Huang X, Chen Y, Liao F, Li L, Xu H. P2-312: The Rps23r1 gene family regulates Alzheimer's beta-amyloid generation and tau phosphorylation Alzheimer's & Dementia. 6: S405-S405. DOI: 10.1016/J.Jalz.2010.05.1363  0.432
2010 Zhang H, Zhang Y, Huang X, Chen Y, Xu H. Appoptosin interacts with amyloid precursor protein and mediates neuronal toxicity via caspase depended pathway Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1262  0.424
2009 Zhang YW, Liu S, Zhang X, Li WB, Chen Y, Huang X, Sun L, Luo W, Netzer WJ, Threadgill R, Wiegand G, Wang R, Cohen SN, Greengard P, Liao FF, ... ... Xu H, et al. A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation. Neuron. 64: 328-40. PMID 19914182 DOI: 10.1016/J.Neuron.2009.08.036  0.661
2009 Dunys J, Sevalle J, Giaime E, Pardossi-Piquard R, Vitek MP, Renbaum P, Levy-Lahad E, Zhang YW, Xu H, Checler F, da Costa CA. p53-dependent control of transactivation of the Pen2 promoter by presenilins. Journal of Cell Science. 122: 4003-8. PMID 19889971 DOI: 10.1242/Jcs.051169  0.442
2009 Ma T, Zhao Y, Kwak YD, Yang Z, Thompson R, Luo Z, Xu H, Liao FF. Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11226-36. PMID 19741129 DOI: 10.1523/Jneurosci.6150-08.2009  0.417
2009 You X, Zhang YW, Chen Y, Huang X, Xu R, Cao X, Chen J, Liu Y, Zhang X, Xu H. Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid. Journal of Neurochemistry. 111: 142-9. PMID 19659691 DOI: 10.1111/J.1471-4159.2009.06312.X  0.47
2009 Liao F, Xu H. Insulin Signaling in Sporadic Alzheimer’s Disease Science Signaling. 2. PMID 19509405 DOI: 10.1126/Scisignal.274Pe36  0.462
2009 Liu Y, Zhang YW, Wang X, Zhang H, You X, Liao FF, Xu H. Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1. The Journal of Biological Chemistry. 284: 12145-52. PMID 19276086 DOI: 10.1074/Jbc.M808497200  0.467
2009 Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith L, Gasparini L, Luo Z, Xu H, Liao FF. Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proceedings of the National Academy of Sciences of the United States of America. 106: 3907-12. PMID 19237574 DOI: 10.1073/Pnas.0807991106  0.456
2008 Bulloj A, Leal MC, Surace EI, Zhang X, Xu H, Ledesma MD, Castaño EM, Morelli L. Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Abeta and insulin degradation. Molecular Neurodegeneration. 3: 22. PMID 19117523 DOI: 10.1186/1750-1326-3-22  0.461
2008 Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG, Sue LI, Woulfe J, Xu H, Stanimirovic DB, Zhang W. Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production. Neurobiology of Disease. 29: 422-37. PMID 18086530 DOI: 10.1016/J.Nbd.2007.10.005  0.475
2008 Zhang YW, Xu H. Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism. Current Molecular Medicine. 7: 687-96. PMID 18045146 DOI: 10.2174/156652407782564462  0.42
2008 Zhang H, Liu R, Wang R, Hong S, Xu H, Zhang Y. Presenilins regulate the cellular level of the tumor suppressor PTEN. Neurobiology of Aging. 29: 653-660. PMID 17222949 DOI: 10.1016/J.Neurobiolaging.2006.11.020  0.547
2008 Xu H, Greenfield JP, Cai D, Leung LW, Kassik K, Rodriguez-Boulan E, Greengard P. Hormonal control of cerebral amyloidogenesis in Alzheimer's diseases Journal of Neurochemistry. 81: 82-82. DOI: 10.1046/J.1471-4159.81.S1.129.X  0.617
2008 Xu H. S4-01-04: Identification and characterization of a novel gene that inhibits GSK3 activity and Abeta production Alzheimer's & Dementia. 4: T177-T178. DOI: 10.1016/J.Jalz.2008.05.475  0.344
2008 Leal MC, Bulloj A, Xu H, Castaño EM, Morelli L. P1-464: Exosome-dependent trafficking of insulin degrading enzyme modulates amyloid beta clearance Alzheimer's & Dementia. 4: T355-T356. DOI: 10.1016/J.Jalz.2008.05.1047  0.321
2007 Gandy S, Zhang YW, Ikin A, Schmidt SD, Bogush A, Levy E, Sheffield R, Nixon RA, Liao FF, Mathews PM, Xu H, Ehrlich ME. Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. Journal of Neurochemistry. 102: 619-26. PMID 17630980 DOI: 10.1111/J.1471-4159.2007.04587.X  0.487
2007 Zhang YW, Wang R, Liu Q, Zhang H, Liao FF, Xu H. Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression. Proceedings of the National Academy of Sciences of the United States of America. 104: 10613-8. PMID 17556541 DOI: 10.1073/Pnas.0703903104  0.444
2007 Li HL, Wang HH, Liu SJ, Deng YQ, Zhang YJ, Tian Q, Wang XC, Chen XQ, Yang Y, Zhang JY, Wang Q, Xu H, Liao FF, Wang JZ. Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 104: 3591-6. PMID 17360687 DOI: 10.1073/Pnas.0609303104  0.477
2007 Lin P, Li F, Zhang YW, Huang H, Tong G, Farquhar MG, Xu H. Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis. Journal of Neurochemistry. 100: 1505-14. PMID 17348862 DOI: 10.1111/J.1471-4159.2006.04336.X  0.534
2007 Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW. Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. The Journal of Biological Chemistry. 282: 10873-80. PMID 17303576 DOI: 10.1074/Jbc.M608856200  0.412
2007 Xu H, Wang R, Zhang YW, Zhang X. Estrogen, beta-amyloid metabolism/trafficking, and Alzheimer's disease. Annals of the New York Academy of Sciences. 1089: 324-42. PMID 17261779 DOI: 10.1196/Annals.1386.036  0.527
2007 Gandy S, Zhang YW, Ikin A, Schmidt SD, Bogush A, Levy E, Sheffield R, Nixon RA, Liao F, Mathews PM, Xu H, Ehrlich ME. Erratum: Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo (Journal of Neurochemistry (2007) 102, (619-626)) Journal of Neurochemistry. 103. DOI: 10.1111/J.1471-4159.2007.04950.X  0.428
2006 He G, Qing H, Cai F, Kwok C, Xu H, Yu G, Bernstein A, Song W. Ubiquitin-proteasome pathway mediates degradation of APH-1. Journal of Neurochemistry. 99: 1403-12. PMID 17059559 DOI: 10.1111/J.1471-4159.2006.04184.X  0.484
2006 Zhang X, Zhang YW, Liu S, Bulloj A, Tong GG, Zhang Z, Liao FF, Xu H. Tumor suppressor PTEN affects tau phosphorylation: deficiency in the phosphatase activity of PTEN increases aggregation of an FTDP-17 mutant Tau. Molecular Neurodegeneration. 1: 7. PMID 16930454 DOI: 10.1186/1750-1326-1-7  0.403
2006 Vetrivel KS, Zhang YW, Xu H, Thinakaran G. Pathological and physiological functions of presenilins. Molecular Neurodegeneration. 1: 4. PMID 16930451 DOI: 10.1186/1750-1326-1-4  0.499
2006 Wang ZF, Li HL, Li XC, Zhang Q, Tian Q, Wang Q, Xu H, Wang JZ. Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture. Journal of Neurochemistry. 98: 1167-75. PMID 16762022 DOI: 10.1111/J.1471-4159.2006.03956.X  0.47
2006 Zhang X, Li F, Bulloj A, Zhang YW, Tong G, Zhang Z, Liao FF, Xu H. Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1272-4. PMID 16645045 DOI: 10.1096/Fj.06-5721Fje  0.494
2006 Wang R, Zhang YW, Sun P, Liu R, Zhang X, Zhang X, Xia K, Xia J, Xu H, Zhang Z. Transcriptional regulation of PEN-2, a key component of the gamma-secretase complex, by CREB. Molecular and Cellular Biology. 26: 1347-54. PMID 16449647 DOI: 10.1128/Mcb.26.4.1347-1354.2006  0.387
2006 Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 103: 1941-6. PMID 16449386 DOI: 10.1073/Pnas.0510708103  0.556
2006 Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 1936-40. PMID 16449385 DOI: 10.1073/Pnas.0510710103  0.768
2006 Bulloj A, Leal MC, Morelli L, Xu H, Castaño E. P1-223: Active insulin degrading enzyme in lipid rafts: Relevance for Aβ degradation in the brain Alzheimer's & Dementia. 2: S161-S162. DOI: 10.1016/J.Jalz.2006.05.600  0.317
2006 Gandy S, Zhang Y, Ikin A, Schmidt S, Sheffield R, Nixon R, Liao F, Matthews P, Xu H, Ehrlich M. S4-03-01: Evidence that aberrant post-TGN trafficking of Alzheimer's APP is sufficient to elevate brain A-beta 42 and may underlie mutant presenilin action Alzheimer's & Dementia. 2: S71-S71. DOI: 10.1016/J.Jalz.2006.05.277  0.411
2006 Xiong H, Callaghan D, Jones A, Yam Y, Pei K, Walker D, Lue L, Woulfe J, Beach TG, Sue L, Stanimiorovic D, Xu H, Zhang W. P4-057: ABCG1/ABCG4-mediated cellular cholesterol efflux affects β-and γ-secretase activities and β-amyloid production in N2a cells Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1795  0.349
2005 Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11542-52. PMID 16354912 DOI: 10.1523/Jneurosci.3831-05.2005  0.527
2005 Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. The Journal of Biological Chemistry. 280: 17020-6. PMID 15711015 DOI: 10.1074/Jbc.M409467200  0.399
2005 Li Z, Wang W, Zhou F, Gao X, Peng G, Xu H, Chen Y. Interaction of stathmin-like 2 protein with the APP intracellular domain Tsinghua Science and Technology. 10: 484-488. DOI: 10.1016/S1007-0214(05)70104-8  0.468
2004 Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. The Journal of Biological Chemistry. 279: 44945-54. PMID 15322084 DOI: 10.1074/Jbc.M407986200  0.387
2004 Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components. The Journal of Biological Chemistry. 279: 40560-6. PMID 15247291 DOI: 10.1074/Jbc.M404345200  0.44
2004 Gasparini L, Rusconi L, Xu H, del Soldato P, Ongini E. Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures. Journal of Neurochemistry. 88: 337-48. PMID 14690522 DOI: 10.1111/J.1471-4159.2004.02154.X  0.474
2003 Liu SJ, Zhang AH, Li HL, Wang Q, Deng HM, Netzer WJ, Xu H, Wang JZ. Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. Journal of Neurochemistry. 87: 1333-44. PMID 14713290 DOI: 10.1046/J.1471-4159.2003.02070.X  0.441
2003 Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits beta-amyloid production but not Notch cleavage. Proceedings of the National Academy of Sciences of the United States of America. 100: 12444-9. PMID 14523244 DOI: 10.1073/Pnas.1534745100  0.57
2003 Gasparini L, Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends in Neurosciences. 26: 404-6. PMID 12900169 DOI: 10.1016/S0166-2236(03)00163-2  0.38
2003 Dou F, Netzer WJ, Tanemura K, Li F, Hartl FU, Takashima A, Gouras GK, Greengard P, Xu H. Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 721-6. PMID 12522269 DOI: 10.1073/Pnas.242720499  0.58
2003 Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, Thinakaran G, Kim TW, Yu G, Xu H. PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. The Journal of Biological Chemistry. 278: 7850-4. PMID 12522139 DOI: 10.1074/Jbc.C200648200  0.387
2003 Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. The Journal of Biological Chemistry. 278: 3446-54. PMID 12435726 DOI: 10.1074/Jbc.M209065200  0.542
2002 Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G. A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface. Neurobiology of Disease. 11: 64-82. PMID 12460547 DOI: 10.1006/Nbdi.2002.0546  0.422
2002 Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. The American Journal of Pathology. 161: 1869-79. PMID 12414533 DOI: 10.1016/S0002-9440(10)64463-X  0.594
2002 Luo Y, Smith JV, Paramasivam V, Burdick A, Curry KJ, Buford JP, Khan I, Netzer WJ, Xu H, Butko P. Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proceedings of the National Academy of Sciences of the United States of America. 99: 12197-202. PMID 12213959 DOI: 10.1073/Pnas.182425199  0.52
2002 Gasparini L, Netzer WJ, Greengard P, Xu H. Does insulin dysfunction play a role in Alzheimer's disease? Trends in Pharmacological Sciences. 23: 288-93. PMID 12084635 DOI: 10.1016/S0165-6147(02)02037-0  0.566
2002 Lu Z, Murray JT, Luo W, Li H, Wu X, Xu H, Backer JM, Chen YG. Transforming growth factor β activates Smad2 in the absence of receptor endocytosis Journal of Biological Chemistry. 277: 29363-29368. PMID 12034739 DOI: 10.1074/Jbc.M203495200  0.332
2002 Leem JY, Vijayan S, Han P, Cai D, Machura M, Lopes KO, Veselits ML, Xu H, Thinakaran G. Presenilin 1 is required for maturation and cell surface accumulation of nicastrin. The Journal of Biological Chemistry. 277: 19236-40. PMID 11943765 DOI: 10.1074/Jbc.C200148200  0.45
2002 Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis. The Journal of Biological Chemistry. 277: 12128-36. PMID 11823458 DOI: 10.1074/Jbc.M110009200  0.569
2001 Yu C, Kim SH, Ikeuchi T, Xu H, Gasparini L, Wang R, Sisodia SS. Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains. The Journal of Biological Chemistry. 276: 43756-60. PMID 11583985 DOI: 10.1074/Jbc.C100410200  0.428
2001 Yan R, Han P, Miao H, Greengard P, Xu H. The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate. The Journal of Biological Chemistry. 276: 36788-96. PMID 11466313 DOI: 10.1074/Jbc.M104350200  0.54
2001 Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H. Stimulation of β-Amyloid Precursor Protein Trafficking by Insulin Reduces Intraneuronal β-Amyloid and Requires Mitogen-Activated Protein Kinase Signaling The Journal of Neuroscience. 21: 2561-2570. DOI: 10.1523/Jneurosci.21-08-02561.2001  0.57
2000 Gouras GK, Xu H, Gross RS, Greenfield JP, Hai B, Wang R, Greengard P. Testosterone reduces neuronal secretion of Alzheimer's beta-amyloid peptides. Proceedings of the National Academy of Sciences of the United States of America. 97: 1202-5. PMID 10655508 DOI: 10.1073/Pnas.97.3.1202  0.59
2000 Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, Relkin NR. Intraneuronal Abeta42 accumulation in human brain. The American Journal of Pathology. 156: 15-20. PMID 10623648 DOI: 10.1016/S0002-9440(10)64700-1  0.683
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2000 Gasparini L, Gouras GK, Wang R, Gross RS, Beal M, Greengard P, Xu H. Insulin-regulated β-amyloid protein trafficking: Stimulated secretion and reduced intracellular accumulation of Aβ in neuronal cell cultures Neurobiology of Aging. 21: 183. DOI: 10.1016/S0197-4580(00)82165-X  0.436
1999 Greenfield JP, Xu H, Greengard P, Gandy S, Seeger M. Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein. The Journal of Biological Chemistry. 274: 33843-6. PMID 10567340 DOI: 10.1074/Jbc.274.48.33843  0.534
1999 Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F, Sisodia SS, Greengard P, Xu H. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proceedings of the National Academy of Sciences of the United States of America. 96: 742-7. PMID 9892704 DOI: 10.1073/Pnas.96.2.742  0.568
1998 Gouras GK, Xu H, Jovanovic JN, Buxbaum JD, Wang R, Greengard P, Relkin NR, Gandy S. Generation and regulation of beta-amyloid peptide variants by neurons. Journal of Neurochemistry. 71: 1920-5. PMID 9798916 DOI: 10.1046/J.1471-4159.1998.71051920.X  0.773
1998 Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, et al. Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nature Medicine. 4: 447-51. PMID 9546791 DOI: 10.1038/Nm0498-447  0.706
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1996 Müsch A, Xu H, Shields D, Rodriguez-Boulan E. Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells. The Journal of Cell Biology. 133: 543-58. PMID 8636230 DOI: 10.1083/Jcb.133.3.543  0.312
1996 Xu H, Sweeney D, Greengard P, Gandy S. Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 93: 4081-4. PMID 8633020 DOI: 10.1073/Pnas.93.9.4081  0.749
1996 Xu H, Sweeney D, Wang R, Sisodia S, Grecngard P, Gandy S. 323 Regulation of Alzheimer β-amyloid protein precursor metabolism in cell-free systems Neurobiology of Aging. 17: S81. DOI: 10.1016/S0197-4580(96)80325-3  0.741
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1995 Xu H, Greengard P, Gandy S. Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein. The Journal of Biological Chemistry. 270: 23243-5. PMID 7559474 DOI: 10.1074/Jbc.270.40.23243  0.538
1993 Xu H, Shields D. Prohormone processing in the trans-Golgi network: endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cells. The Journal of Cell Biology. 122: 1169-84. PMID 8104189 DOI: 10.1083/Jcb.122.6.1169  0.664
Low-probability matches (unlikely to be authored by this person)
2006 Zhang X, Li F, Bulloj A, Zhang Y, Tong G, Zhang Z, Liao F, Xu H. O2-01-05: Tumor suppressor PTEN affects tau phosphorylation, aggregation and binding to microtubules Alzheimer's & Dementia. 2: S30-S31. DOI: 10.1016/J.Jalz.2006.05.106  0.298
2013 Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy Nature Reviews Neurology. DOI: 10.1038/Nrneurol.2013.32  0.297
2007 Zhang YW, Xu H. Alteration of beta-secretase traffic by the receptor tyrosine kinase signaling pathway - a new mechanism for regulating Alzheimer's beta-amyloid production. Cell Research. 17: 385-6. PMID 17496905 DOI: 10.1038/cr.2007.41  0.297
2022 Feng T, Niu M, Ji C, Gao Y, Wen J, Bu G, Xu H, Zhang YW. Correction to: SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation. Molecular Neurobiology. PMID 36322338 DOI: 10.1007/s12035-022-03097-7  0.291
2016 Zhong L, Xie YZ, Cao TT, Wang Z, Wang T, Li X, Shen RC, Xu H, Bu G, Chen XF. A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism. Molecular Neurodegeneration. 11: 2. PMID 26754117 DOI: 10.1186/S13024-016-0069-4  0.289
2015 Chen XF, Wei Z, Wang T, Zhang ZL, Wang Y, Heckman MG, Diehl NN, Zhang YW, Xu H, Bu G. Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students. Plos One. 10: e0143157. PMID 26574747 DOI: 10.1371/Journal.Pone.0143157  0.282
2006 Wang R, Zhang YW, Zhang X, Liu R, Zhang X, Hong S, Xia K, Xia J, Zhang Z, Xu H. Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1275-7. PMID 16645044 DOI: 10.1096/fj.06-5839fje  0.266
2021 Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q. Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing. Molecular Neurodegeneration. 16: 66. PMID 34551807 DOI: 10.1186/s13024-021-00485-w  0.264
2014 Niu M, Hu J, Wu S, Xiaoe Z, Xu H, Zhang Y, Zhang J, Yang Y. Structural bioinformatics-based identification of EGFR inhibitor gefitinib as a putative lead compound for BACE. Chemical Biology & Drug Design. 83: 81-8. PMID 24516878 DOI: 10.1111/cbdd.12200  0.259
2016 Kang R, Li P, Wang T, Li X, Wei Z, Zhang Z, Zhong L, Cao L, Heckman MG, Zhang YW, Xu H, Huang C, Bu G, Chen XF. Apolipoprotein E epsilon 2 allele and low serum cholesterol as risk factors for gastric cancer in a Chinese Han population. Scientific Reports. 6: 19930. PMID 26817942 DOI: 10.1038/Srep19930  0.254
2006 Zhang Y, Wang R, Sun P, Zhang X, Liu R, Zhang X, Hong S, Xia K, Xia J, Zhang Z, Xu H. P1-298: Differential transcriptional regulation of PEN-2 and APH-1A, two key components of the gamma-secretase complex Alzheimer's & Dementia. 2: S184-S184. DOI: 10.1016/J.Jalz.2006.05.675  0.251
2023 Wang Z, Niu M, Zheng N, Meng J, Jiang Y, Yang D, Yao P, Yao T, Luo H, Xu H, Ge Y, Zhang YW, Zhang X. Increased level of RAB39B leads to neuronal dysfunction and behavioural changes in mice. Journal of Cellular and Molecular Medicine. PMID 36977207 DOI: 10.1111/jcmm.17704  0.249
2022 Zhang H, Shao L, Lin Z, Long QX, Yuan H, Cai L, Jiang G, Guo X, Yang R, Zhang Z, Zhang B, Liu F, Li Z, Ma Q, Zhang YW, ... ... Xu H, et al. APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients. Signal Transduction and Targeted Therapy. 7: 261. PMID 35915083 DOI: 10.1038/s41392-022-01118-4  0.249
2021 Wei Y, Ma M, Lin S, Li X, Shu Y, Wang Z, Zhou Y, Hu B, Cheng B, Duan S, Huang X, Xu H, Zhang YW, Zheng H. Proteolytic Shedding of Human Colony-Stimulating Factor 1 Receptor and its implication. Journal of Cellular and Molecular Medicine. PMID 33783963 DOI: 10.1111/jcmm.16474  0.248
2022 Zhao Y, Xu H. Microglial lactate metabolism as a potential therapeutic target for Alzheimer's disease. Molecular Neurodegeneration. 17: 36. PMID 35550609 DOI: 10.1186/s13024-022-00541-z  0.245
2022 Meng J, Han L, Zheng N, Wang T, Xu H, Jiang Y, Wang Z, Liu Z, Zheng Q, Zhang X, Luo H, Can D, Lu J, Xu H, Zhang YW. Microglial Deficiency Impairs Phagocytosis of Synapse and Leads to Autism-Like Behaviors in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35606143 DOI: 10.1523/JNEUROSCI.1644-21.2022  0.245
2014 Zheng H, Tang R, Yao Y, Ji Z, Cao Y, Liu Z, Peng F, Wang W, Can D, Xing H, Bu G, Xu H, Zhang YW, Zheng W. MiR-219 Protects Against Seizure in the Kainic Acid Model of Epilepsy. Molecular Neurobiology. PMID 25394384 DOI: 10.1007/S12035-014-8981-5  0.244
2015 Cao L, Zhou J, Zhang J, Wu S, Yang X, Zhao X, Li H, Luo M, Yu Q, Lin G, Lin H, Xie J, Li P, Hu X, Zheng C, ... ... Xu H, et al. Cyclin-dependent kinase 5 decreases in gastric cancer and its nuclear accumulation suppresses gastric tumorigenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1419-28. PMID 25609066 DOI: 10.1158/1078-0432.Ccr-14-1950  0.236
2017 Yu Y, Su Z, Wang Z, Xu H. USP7 is associated with greater disease activity in systemic lupus erythematosus via stabilization of the IFNα receptor. Molecular Medicine Reports. PMID 28656291 DOI: 10.3892/mmr.2017.6819  0.228
2020 Huo Y, Gao Y, Zheng Q, Zhao D, Guo T, Zhang S, Zeng Y, Cheng Y, Gu H, Zhang L, Zhu B, Luo H, Zhang X, Zhou Y, Zhang YW, ... ... Xu H, et al. Overexpression of Human Enhances Learning and Memory Through Modulating Synaptic Plasticity in Mice. Frontiers in Cell and Developmental Biology. 8: 595357. PMID 33330482 DOI: 10.3389/fcell.2020.595357  0.227
2000 Greenfield JP, Gross RS, Gouras GK, Leung L, Rodriguez-Boulan E, Kaasik K, Greengard P, Xu H. Molecular and cellular basis for the anti-amyloidogenic effects of estrogen Neurobiology of Aging. 21: 190. DOI: 10.1016/S0197-4580(00)82198-3  0.225
2020 Niu M, Zheng N, Wang Z, Gao Y, Luo X, Chen Z, Fu X, Wang Y, Wang T, Liu M, Yao T, Yao P, Meng J, Zhou Y, Ge Y, ... ... Xu H, et al. RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy. Frontiers in Cell and Developmental Biology. 8: 598622. PMID 33364235 DOI: 10.3389/fcell.2020.598622  0.223
2013 Xing H, Zheng H, Wang J, Qiu J, Qiao Z, Peng Z, Shao Y, Xu H, Bu G. Increased menin expression associated with neural apoptosis in the frontal cortex of SIV infected macaques Journal of the Neurological Sciences. 333: e349-e350. DOI: 10.1016/J.Jns.2013.07.1285  0.222
2010 Cui D, Wang S, Chen Y, Tong J, Ma J, Tang L, Yang X, Shi Y, Tian J, Lu L, Xu H. An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand. Cellular & Molecular Immunology. 7: 316-22. PMID 20228835 DOI: 10.1038/Cmi.2010.7  0.22
2022 Leng L, Yuan Z, Pan R, Su X, Wang H, Xue J, Zhuang K, Gao J, Chen Z, Lin H, Xie W, Li H, Chen Z, Ren K, Zhang X, ... ... Xu H, et al. Author Correction: Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance. Nature Metabolism. PMID 36241712 DOI: 10.1038/s42255-022-00682-x  0.219
2023 Li X, Hu B, Guan X, Wang Z, Zhou Y, Sun H, Zhang X, Li Y, Huang X, Zhao Y, Wang X, Xu H, Zhang YW, Wang Z, Zheng H. Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). Journal of Neuroinflammation. 20: 134. PMID 37259140 DOI: 10.1186/s12974-023-02774-1  0.217
2015 Su Z, Wang T, Zhu H, Zhang P, Han R, Liu Y, Ni P, Shen H, Xu W, Xu H. HMGB1 modulates Lewis cell autophagy and promotes cell survival via RAGE-HMGB1-Erk1/2 positive feedback during nutrient depletion. Immunobiology. 220: 539-44. PMID 25578401 DOI: 10.1016/j.imbio.2014.12.009  0.216
2020 Tian J, Hong Y, Zhu Q, Zhou H, Zhang Y, Shen Z, Guo H, Zhang Y, Ai X, Zhao F, Rui K, Xu H, Wang S. Mesenchymal Stem Cell Enhances the Function of MDSCs in Experimental Sjögren Syndrome. Frontiers in Immunology. 11: 604607. PMID 33414787 DOI: 10.3389/fimmu.2020.604607  0.214
2020 Tian Y, Cao Y, Chen R, Jing Y, Xia L, Zhang S, Xu H, Su Z. HMGB1 A Box protects neurons by potently inhibiting both microglia and T cell-mediated inflammation in a mouse Parkinson's Disease model. Clinical Science (London, England : 1979). PMID 32706028 DOI: 10.1042/CS20200553  0.212
2023 Zhang W, Ding L, Chen H, Zhang M, Ma R, Zheng S, Gong J, Zhang Z, Xu H, Xu P, Zhang Y. Cntnap4 partial deficiency exacerbates α-synuclein pathology through astrocyte-microglia C3-C3aR pathway. Cell Death & Disease. 14: 285. PMID 37087484 DOI: 10.1038/s41419-023-05807-y  0.212
2019 Tian J, Rui K, Hong Y, Wang X, Xiao F, Lin X, Ma J, Guo H, Xu H, Ma K, Xu D, Liu D, Zhao Y, Lu L, Wang S. Increased GITRL Impairs the Function of Myeloid-Derived Suppressor Cells and Exacerbates Primary Sjögren Syndrome. Journal of Immunology (Baltimore, Md. : 1950). PMID 30760623 DOI: 10.4049/Jimmunol.1801051  0.209
2022 Zhang H, Zheng Q, Guo T, Zhang S, Zheng S, Wang R, Deng Q, Yang G, Zhang S, Tang L, Qi Q, Zhu L, Zhang XF, Luo H, Zhang X, ... ... Xu H, et al. Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability. Molecular Psychiatry. PMID 35338313 DOI: 10.1038/s41380-022-01521-x  0.209
2021 Rui K, Hong Y, Zhu Q, Shi X, Xiao F, Fu H, Yin Q, Xing Y, Wu X, Kong X, Xu H, Tian J, Wang S, Lu L. Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren's syndrome by modulating the function of myeloid-derived suppressor cells. Cellular & Molecular Immunology. PMID 33408339 DOI: 10.1038/s41423-020-00587-3  0.208
2011 Yao G, Zong Y, Gu S, Zhou J, Xu H, Mathews II, Jin R. Crystal structure of the glutamate receptor GluA1 N-terminal domain. The Biochemical Journal. 438: 255-63. PMID 21639859 DOI: 10.1042/Bj20110801  0.207
2016 Ma J, Feng D, Wei Y, Tian J, Tang X, Rui K, Lu L, Xu H, Wang S. Blockade of Glucocorticoid-Induced Tumor Necrosis Factor-Receptor-Related Protein Signaling Ameliorates Murine Collagen-Induced Arthritis by Modulating Follicular Helper T Cells. The American Journal of Pathology. PMID 27106763 DOI: 10.1016/J.Ajpath.2016.02.010  0.206
2019 Shomali N, Baradaran B, Deljavan Ghodrati M, Akbari M, Hemmatzadeh M, Mohammadi H, Jang Y, Xu H, Sandoghchian Shotorbani S. A new insight into thymosin β4, a promising therapeutic approach for neurodegenerative disorders. Journal of Cellular Physiology. PMID 31612500 DOI: 10.1002/jcp.29293  0.205
2021 Gong J, Zhang W, Ding L, Zhang M, Zheng S, Ma R, Tang J, Yi W, Xu H, Zhang Y. 4,4'-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson's disease therapy. Free Radical Biology & Medicine. PMID 34332078 DOI: 10.1016/j.freeradbiomed.2021.07.038  0.204
2015 Shen P, Su Z, Wang T, Liu Y, Zhao Y, Han Q, Xu H, Wang S. Expression and purification of the mGITR-Fc fusion protein and its effect on CD4⁺ T cells and dendritic cells in vitro. Molecular Medicine Reports. 12: 3965-71. PMID 26018202 DOI: 10.3892/mmr.2015.3846  0.195
2011 Kong F, Su Z, Zhou C, Sun C, Liu Y, Zheng D, Yuan H, Yin J, Fang J, Wang S, Xu H. Role of positive selection in functional divergence of mammalian neuronal apoptosis inhibitor proteins during evolution. Journal of Biomedicine & Biotechnology. 2011: 809765. PMID 22131819 DOI: 10.1155/2011/809765  0.193
2023 Wang Z, Yang D, Jiang Y, Wang Y, Niu M, Wang C, Luo H, Xu H, Li J, Zhang YW, Zhang X. Loss of RAB39B does not alter MPTP-induced Parkinson's disease-like phenotypes in mice. Frontiers in Aging Neuroscience. 15: 1087823. PMID 36761179 DOI: 10.3389/fnagi.2023.1087823  0.192
2017 Richard SA, Jiang Y, Xiang LH, Zhou S, Wang J, Su Z, Xu H. Post-translational modifications of high mobility group box 1 and cancer. American Journal of Translational Research. 9: 5181-5196. PMID 29312476  0.189
2013 Wang Y, Zheng D, Wei M, Ma J, Yu Y, Chen R, Lacefield JC, Xu H, Peng T. Over-expression of calpastatin aggravates cardiotoxicity induced by doxorubicin. Cardiovascular Research. 98: 381-90. PMID 23455548 DOI: 10.1093/cvr/cvt048  0.185
2020 Tian X, Zheng Y, Yin K, Ma J, Tian J, Zhang Y, Mao L, Xu H, Wang S. LncRNA AK036396 inhibits maturation and accelerates immunosuppression of polymorphonuclear myeloid-derived suppressor cells by enhancing the stability of ficolin B. Cancer Immunology Research. PMID 32102837 DOI: 10.1158/2326-6066.Cir-19-0595  0.184
2018 Jiang Y, Chen R, Shao X, Ji X, Lu H, Zhou S, Zong G, Xu H, Su Z. HMGB1 silencing in macrophages prevented their functional skewing and ameliorated EAM development: Nuclear HMGB1 may be a checkpoint molecule of macrophage reprogramming. International Immunopharmacology. 56: 277-284. PMID 29414662 DOI: 10.1016/j.intimp.2018.01.013  0.183
2003 Dou F, Netzer WJ, Takashima A, Xu H. Heat shock proteins reduce aggregation and facilitate degradation of tau protein International Congress Series. 1252: 383-393. DOI: 10.1016/S0531-5131(03)00077-3  0.182
2017 Seidu RA, Wu M, Su Z, Xu H. Paradoxical Role of High Mobility Group Box 1 in Glioma: A Suppressor or a Promoter? Oncology Reviews. 11: 325. PMID 28382190 DOI: 10.4081/oncol.2017.325  0.179
2015 Tang X, Tian J, Ma J, Wang J, Qi C, Rui K, Wang Y, Xu H, Lu L, Wang S. GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis. Oncotarget. PMID 26657118 DOI: 10.18632/Oncotarget.6535  0.175
2011 Wang M, Luo Z, Du H, Xu S, Ni B, Zhang H, Sheng X, Xu H, Huang X. Molecular characterization of a functional type VI secretion system in Salmonella enterica serovar Typhi. Current Microbiology. 63: 22-31. PMID 21487806 DOI: 10.1007/s00284-011-9935-z  0.174
2013 Tian J, Ma J, Ma K, Guo H, Baidoo SE, Zhang Y, Yan J, Lu L, Xu H, Wang S. β-Glucan enhances antitumor immune responses by regulating differentiation and function of monocytic myeloid-derived suppressor cells. European Journal of Immunology. 43: 1220-30. PMID 23424024 DOI: 10.1002/Eji.201242841  0.173
2023 Vatandoust SM, Mahmoudi J, Oryan S, Farajdokht F, Sadigh-Eteghad S, Shotorbani SS, Xu H, Esfahani DE. Sericin improves memory and sociability impairments evoked by transient global cerebral ischemia through suppression of hippocampal oxidative stress, inflammation, and apoptosis. The Chinese Journal of Physiology. 66: 209-219. PMID 37635480 DOI: 10.4103/cjop.CJOP-D-23-00006  0.17
2011 Shotorbani SS, Su ZL, Xu HX. Toll-like receptors are potential therapeutic targets in rheumatoid arthritis. World Journal of Biological Chemistry. 2: 167-72. PMID 21912729 DOI: 10.4331/wjbc.v2.i7.167  0.169
2015 Tian X, Tian J, Tang X, Rui K, Zhang Y, Ma J, Wang Y, Xu H, Lu L, Wang S. Particulate β-glucan regulates the immunosuppression of granulocytic myeloid-derived suppressor cells by inhibiting NFIA expression. Oncoimmunology. 4: e1038687. PMID 26405609 DOI: 10.1080/2162402X.2015.1038687  0.169
2001 Bai L, Xu H, Collins JF, Ghishan FK. Molecular and Functional Analysis of a Novel Neuronal Vesicular Glutamate Transporter Journal of Biological Chemistry. 276: 36764-36769. PMID 11432869 DOI: 10.1074/Jbc.M104578200  0.167
2021 Song G, Zhang Y, Tian J, Ma J, Yin K, Xu H, Wang S. TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host. Frontiers in Immunology. 12: 649020. PMID 33717204 DOI: 10.3389/fimmu.2021.649020  0.165
2015 Ni P, Zhang Y, Liu Y, Lin X, Su X, Lu H, Shen H, Xu W, Xu H, Su Z. HMGB1 silence could promote MCF-7 cell apoptosis and inhibit invasion and metastasis. International Journal of Clinical and Experimental Pathology. 8: 15940-6. PMID 26884867  0.164
2022 Liu FR, Zhou Y, Wang Y, Huang LL, Zhang X, Luo H, Wu SY, Lyu HY, Huang LH, Xu H, Zhang YW. Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorder. Translational Psychiatry. 12: 390. PMID 36115840 DOI: 10.1038/s41398-022-02163-x  0.164
2017 Tang J, Raza A, Chen J, Xu H. A Systematic Review on the Sinomenine Derivatives. Mini Reviews in Medicinal Chemistry. PMID 29173167 DOI: 10.2174/1389557517666171123212557  0.163
2012 Wang S, Shi Y, Yang M, Ma J, Tian J, Chen J, Mao C, Jiao Z, Ko KH, Baidoo SE, Xu H, Hua Z, Lu L. Glucocorticoid-induced tumor necrosis factor receptor family-related protein exacerbates collagen-induced arthritis by enhancing the expansion of Th17 cells. The American Journal of Pathology. 180: 1059-67. PMID 22214837 DOI: 10.1016/J.Ajpath.2011.11.018  0.162
2014 Chen H, Lu Q, Zhang Y, Zhang C, Zhang H, Xu H. Overexpression of SLC25A38 protein on acute lymphoblastic leukemia cells. Oncology Letters. 7: 1422-1426. PMID 24765149 DOI: 10.3892/ol.2014.1947  0.162
2021 Lu W, Cao F, Feng L, Song G, Chang Y, Chu Y, Chen Z, Shen B, Xu H, Wang S, Ma J. LncRNA Snhg6 regulates the differentiation of MDSCs by regulating the ubiquitination of EZH2. Journal of Hematology & Oncology. 14: 196. PMID 34794493 DOI: 10.1186/s13045-021-01212-0  0.16
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2019 Xiong S, Peng H, Ding X, Wang X, Wang L, Wu C, Wang S, Xu H, Liu Y. Circular RNA Expression Profiling and the Potential Role of hsa_circ_0089172 in Hashimoto's Thyroiditis via Sponging miR125a-3p. Molecular Therapy. Nucleic Acids. 17: 38-48. PMID 31207490 DOI: 10.1016/j.omtn.2019.05.004  0.074
2012 Chen J, Tong J, Liu H, Liu Y, Su Z, Wang S, Shi Y, Zheng D, Sandoghchian S, Geng J, Xu H. Increased frequency of Th17 cells in the peripheral blood of children infected with enterovirus 71. Journal of Medical Virology. 84: 763-7. PMID 22431024 DOI: 10.1002/jmv.23254  0.074
2012 Shi Y, Sandoghchian Shotorbani S, Su Z, Liu Y, Tong J, Zheng D, Chen J, Liu Y, Xu Y, Jiao Z, Wang S, Lu L, Huang X, Xu H. Enhanced HMGB1 expression may contribute to Th17 cells activation in rheumatoid arthritis. Clinical & Developmental Immunology. 2012: 295081. PMID 22110531 DOI: 10.1155/2012/295081  0.074
2019 Zhu D, Tian J, Wu X, Li M, Tang X, Rui K, Guo H, Ma J, Xu H, Wang S. G-MDSC-derived exosomes attenuate collagen-induced arthritis by impairing Th1 and Th17 cell responses. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165540. PMID 31470074 DOI: 10.1016/J.Bbadis.2019.165540  0.074
2009 Gong Y, Chen N, Wang FQ, Wang ZH, Xu HX. Serum proteome alteration of severe sepsis in the treatment of continuous renal replacement therapy Nephrology Dialysis Transplantation. 24: 3108-3114. PMID 19461007 DOI: 10.1093/Ndt/Gfp231  0.073
2015 Su Z, Lu H, Jiang H, Zhu H, Li Z, Zhang P, Ni P, Shen H, Xu W, Xu H. IFN-γ-producing Th17 cells bias by HMGB1-T-bet/RUNX3 axis might contribute to progression of coronary artery atherosclerosis. Atherosclerosis. 243: 421-428. PMID 26520896 DOI: 10.1016/j.atherosclerosis.2015.09.037  0.073
2001 Bai L, Collins JF, Xu H, Ghishan FK. Transcriptional regulation of rat Na(+)/H(+) exchanger isoform-2 (NHE-2) gene by Sp1 transcription factor. American Journal of Physiology. Cell Physiology. 280: C1168-75. PMID 11287330 DOI: 10.1152/Ajpcell.2001.280.5.C1168  0.073
2006 Wang S, Xu H, Wang Y, Ma J, Mao C, Shao Q, Ma B, Xu W, Yang S. Regulatory T cells induced by rAAV carrying the forkhead box P3 gene prevent autoimmune thyroiditis in mice. International Journal of Molecular Medicine. 18: 1193-9. PMID 17089026  0.072
2024 Zheng D, Sun Q, Su Z, Kong F, Shi X, Tong J, Shen P, Peng T, Wang S, Xu H. Correction: Enhancing Specific-Antibody Production to the ragB Vaccine with GITRL That Expand Tfh, IFN-γ+ T Cells and Attenuates Porphyromonas gingivalis Infection in Mice. Plos One. 19: e0301151. PMID 38507351 DOI: 10.1371/journal.pone.0301151  0.072
2020 Chang Y, Lu W, Chu Y, Yan J, Wang S, Xu H, Ma H, Ma J. Extraction of polysaccharides from maca: Characterization and immunoregulatory effects on CD4 T cells. International Journal of Biological Macromolecules. PMID 32179120 DOI: 10.1016/j.ijbiomac.2020.03.098  0.07
2011 Jiang XG, Chen SX, Wu L, Xu HX. [Effects of oral type II collagen on serum antibody and the cytokine cxpression in Peyer's patches]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 27: 621-5. PMID 21651860  0.069
2021 Azar MRMH, Aghazadeh H, Mohammed HN, Sara MRS, Hosseini A, Shomali N, Tamjidifar R, Tarzi S, Mansouri M, Sarand SP, Marofi F, Akbari M, Xu H, Shotorbani SS. miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4. International Immunopharmacology. 92: 107355. PMID 33429333 DOI: 10.1016/j.intimp.2020.107355  0.069
2015 Chen X, Su Z, Wang S, Xu H. Clinical and prognostic significance of Arl4c expression in colorectal cancer. Cancer Biomarkers : Section a of Disease Markers. PMID 26756615 DOI: 10.3233/CBM-150562  0.067
2012 Chen D, Hu Q, Mao C, Jiao Z, Wang S, Yu L, Xu Y, Dai D, Yin L, Xu H. Increased IL-17-producing CD4(+) T cells in patients with esophageal cancer. Cellular Immunology. 272: 166-74. PMID 22082565 DOI: 10.1016/j.cellimm.2011.10.015  0.067
2010 Mao F, Xu WR, Qian H, Zhu W, Yan YM, Shao QX, Xu HX. Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 59: 219-25. PMID 19763787 DOI: 10.1007/s00011-009-0090-y  0.066
2012 Su ZL, Wang YM, Liu YF, Wang T, Tian SS, Zhang P, Ji XY, Ma K, Xu HX. [Effect of IL-17 on collagen I/III expression in cardiac fibroblasts isolated from BALB/c mice]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 28: 897-8, 902. PMID 22980648  0.065
2012 Wang W, Shao S, Jiao Z, Guo M, Xu H, Wang S. The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis. Rheumatology International. 32: 887-93. PMID 21221592 DOI: 10.1007/s00296-010-1710-0  0.065
2017 Zhang Y, Ng W, Hu J, Mussa SS, Ge Y, Xu H. Formulation and in vitro stability evaluation of ethosomal carbomer hydrogel for transdermal vaccine delivery. Colloids and Surfaces. B, Biointerfaces. 163: 184-191. PMID 29294420 DOI: 10.1016/j.colsurfb.2017.12.031  0.065
2022 Lu J, Wu J, Mao L, Xu H, Wang S. Revisiting PD-1/PD-L pathway in T and B cell response: Beyond immunosuppression. Cytokine & Growth Factor Reviews. PMID 35850949 DOI: 10.1016/j.cytogfr.2022.07.003  0.065
2014 Bie Q, Zhang P, Su Z, Zheng D, Ying X, Wu Y, Yang H, Chen D, Wang S, Xu H. Polarization of ILC2s in peripheral blood might contribute to immunosuppressive microenvironment in patients with gastric cancer. Journal of Immunology Research. 2014: 923135. PMID 24741632 DOI: 10.1155/2014/923135  0.064
2011 Sun X, Cai H, Qian H, Zhu W, Yan Y, Xu H, Xu W. Mesenchymal stem cells isolated from human uterine cervix cancer tissues. Cell Biology International. 35: 119-23. PMID 20874707 DOI: 10.1042/CBI20100132  0.063
2010 Chen JG, Su ZL, Liu YZ, Wang SJ, Liu XX, Shao QX, Xu HX. [Construction of MyD88-Pseudomonas aeruginosa epitope DNA vaccine and its expression in eukaryotic cells]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 25: 193-5. PMID 19257978  0.063
2011 Ma J, Tian J, Liu Y, Liu QL, Mao ZM, Jiao ZJ, Xu HX, Wang SJ. [Construction and identification of recombinant adenovirus vector pAdEasy-GFP-GITRL]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 26: 1075-7. PMID 21055344  0.062
2021 Gong J, Xu H. Current Perspectives on the Role of Nrf2 in 5-Fluorouracil Resistance in Colorectal Cancer. Anti-Cancer Agents in Medicinal Chemistry. PMID 33511942 DOI: 10.2174/1871520621666210129094354  0.062
2018 Wu Y, Yue J, Wu J, Zhou W, Li D, Ding K, Barnie PA, Xu X, Xu H, Shi W. Obesity May Provide Pro-ILC3 Development Inflammatory Environment in Asthmatic Children. Journal of Immunology Research. 2018: 1628620. PMID 30622974 DOI: 10.1155/2018/1628620  0.061
2015 Barnie PA, Lin X, Liu Y, Xu H, Su Z. IL-17 producing innate lymphoid cells 3 (ILC3) but not Th17 cells might be the potential danger factor for preeclampsia and other pregnancy associated diseases. International Journal of Clinical and Experimental Pathology. 8: 11100-7. PMID 26617829  0.061
2020 Wan J, Wu Y, Ji X, Huang L, Cai W, Su Z, Wang S, Xu H. IL-9 and IL-9-producing cells in tumor immunity. Cell Communication and Signaling : Ccs. 18: 50. PMID 32228589 DOI: 10.1186/s12964-020-00538-5  0.061
2022 Wang J, Zhang Y, Yin K, Xu P, Tian J, Ma J, Tian X, Wang Y, Tang X, Xu H, Wang S. Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice. Oncotarget. 13: 425. PMID 35198101 DOI: 10.18632/oncotarget.28052  0.061
2008 Xu S, Zhang H, Sheng X, Xu H, Huang X. Transcriptional expression of fljB:z66, a flagellin gene located on a novel linear plasmid of Salmonella enterica serovar Typhi under environmental stresses. The New Microbiologica. 31: 241-7. PMID 18623990  0.06
2020 Kesavan D, Vasudevan A, Wu L, Chen J, Su Z, Wang S, Xu H. Integrative analysis of outer membrane vesicles proteomics and whole-cell transcriptome analysis of eravacycline induced Acinetobacter baumannii strains. Bmc Microbiology. 20: 31. PMID 32046644 DOI: 10.1186/s12866-020-1722-1  0.06
2015 Xia S, Li XP, Cheng L, Han MT, Zhang MM, Shao QX, Xu HX, Qi L. Fish Oil-Rich Diet Promotes Hematopoiesis and Alters Hematopoietic Niche. Endocrinology. 156: 2821-30. PMID 26061726 DOI: 10.1210/En.2015-1258  0.059
2011 Zhang H, Jiao ZJ, Mao CM, Jiang Q, Tong J, Wang SJ, Xu HX. [A preliminary study on the effect of lincomycin on the immune function of dendritic cell line DC2.4]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 27: 763-6. PMID 21722529  0.059
2012 Jiao ZJ, Gao JJ, Hua SH, Chen DY, Wang WH, Wang H, Wang XH, Xu HX. Correlation between circulating myeloid-derived suppressor cells and Th17 cells in esophageal cancer. World Journal of Gastroenterology : Wjg. 18: 5454-61. PMID 23082063 DOI: 10.3748/wjg.v18.i38.5454  0.058
2015 Wang H, Hara Y, Liu X, Reuben JM, Xie Y, Xu H, Bu G, Pei Y, Gupta V, Wu X. Detection and enumeration of circulating tumor cells based on their invasive property. Oncotarget. PMID 26247814 DOI: 10.18632/oncotarget.4454  0.058
2022 Vasudevan A, Kesavan DK, Wu L, Su Z, Wang S, Ramasamy MK, Hopper W, Xu H. and Screening of Natural Compounds as Broad-Spectrum -Lactamase Inhibitors against New Delhi Metallo--lactamase-1 (NDM-1). Biomed Research International. 2022: 4230788. PMID 35372567 DOI: 10.1155/2022/4230788  0.057
2008 Mao C, Wang S, Jiang Q, Tong J, Ma J, Yang M, Xu X, Qiu G, Shao Q, Li L, Xu H. Increased CD4CD25+FOXP3+ regulatory T Cells in cancer patients from conversion of CD4+CD25- T cells through tumor-derived factors. Onkologie. 31: 243-8. PMID 18497513 DOI: 10.1159/000121360  0.057
2012 Sun CX, Liu YF, Zhou CL, Chen P, Zhang P, Su ZL, Zhu CP, Wang SJ, Xu HX. [The pathogenesis of CD4(+)T cells infiltrated into the spinal cord in rat SNL model]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 27: 1291-4. PMID 22152807  0.056
2021 Wan J, Wu Y, Huang L, Tian Y, Ji X, Abdelaziz MH, Cai W, Dineshkumar K, Lei Y, Yao S, Sun C, Su Z, Wang S, Xu H. ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8 T cells. Cancer Letters. PMID 33429004 DOI: 10.1016/j.canlet.2021.01.002  0.056
2022 Su Z, Zhang P, Yu Y, Lu H, Liu Y, Ni P, Su X, Wang D, Liu Y, Wang J, Shen H, Xu W, Xu H. Retraction Note: HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development. Scientific Reports. 12: 5931. PMID 35396497 DOI: 10.1038/s41598-022-10210-2  0.054
2010 Zhang H, Ma L, Turner M, Xu H, Zheng X, Dong Y, Jiang S. Salicylic acid enhances biocontrol efficacy of Rhodotorula glutinis against postharvest Rhizopus rot of strawberries and the possible mechanisms involved Food Chemistry. 122: 577-583. DOI: 10.1016/J.FOODCHEM.2010.03.013  0.053
2019 Tian X, Ma J, Wang T, Tian J, Zhang Y, Mao L, Xu H, Wang S. Corrigendum: Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer. Frontiers in Immunology. 10: 2929. PMID 32038606 DOI: 10.3389/fimmu.2019.02929  0.052
2014 Bu G, Xu H. Reviewer acknowledgement Molecular Neurodegeneration. DOI: 10.1186/1750-1326-9-9  0.051
2021 Yu Y, Tan P, Zhuang Z, Wang Z, Zhu L, Qiu R, Xu H. DIA proteomics analysis through serum profiles reveals the significant proteins as candidate biomarkers in women with PCOS. Bmc Medical Genomics. 14: 125. PMID 33964924 DOI: 10.1186/s12920-021-00962-7  0.051
2009 Xu H, Su Z, Wang S, Dai X, Chen J, Kong F, Li Y, Peng S, Shao Q, Lu L, Ezaki T. Four novel resistance integron gene-cassette occurrences in bacterial isolates from zhenjiang, china. Current Microbiology. 59: 113-7. PMID 19365688 DOI: 10.1007/s00284-009-9405-z  0.05
2015 Liu Y, Lin X, Bao T, Ni P, Xie C, Shen H, Xu W, Xu H, Su Z. [Detection and correlation analysis of miRNAs and myeloid-derived suppressor cells in ovarian cancer-bearing mice]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 31: 467-9, 473. PMID 25854564  0.05
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2006 Huang X, Xu H, Sha MM, Zhao L, Ohkusu K, Kawamura Y, Ezaki T. Virulence-defective strains of Salmonella enterica serovar Typhi as candidates for education at level 2 facilities. Microbiology and Immunology. 50: 273-9. PMID 16625049 DOI: 10.1111/j.1348-0421.2006.tb03795.x  0.049
2018 Ma J, Xu H, Wang S. Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer. Journal of Immunology Research. 2018: 6319649. PMID 29765990 DOI: 10.1155/2018/6319649  0.048
2021 Abdelaziz MH, Ji X, Wan J, Abouelnazar FA, Abdelwahab SF, Xu H. Mycobacterium-Induced Th1, Helminths-Induced Th2 Cells and the Potential Vaccine Candidates for Allergic Asthma: Imitation of Natural Infection. Frontiers in Immunology. 12: 696734. PMID 34413850 DOI: 10.3389/fimmu.2021.696734  0.048
2014 Chen Y, Tian J, Tian X, Tang X, Rui K, Tong J, Lu L, Xu H, Wang S. Adipose tissue dendritic cells enhances inflammation by prompting the generation of Th17 cells. Plos One. 9: e92450. PMID 24642966 DOI: 10.1371/Journal.Pone.0092450  0.047
2020 Cheng J, Kesavan DK, Vasudevan A, Cai W, Wang H, Su Z, Wang S, Xu H. Genome and Transcriptome Analysis of A. baumannii's "Transient" Increase in Drug Resistance under Tigecycline Pressure. Journal of Global Antimicrobial Resistance. PMID 32084603 DOI: 10.1016/j.jgar.2020.02.003  0.045
2011 Sun C, Su Z, Zhou C, Liu Y, Yuan H, Yin J, Xu H. Complex class 1 integron containing bla ( CTX-M-1 ) genes isolated from Escherichia coli: a potentially novel resistant gene-capturing tool kit. Current Microbiology. 64: 265-70. PMID 22170571 DOI: 10.1007/s00284-011-0062-7  0.043
2010 Chen J, Su Z, Liu Y, Sandoghchian S, Zheng D, Wang S, Xu H. Herbaspirillum species: a potential pathogenic bacteria isolated from acute lymphoblastic leukemia patient. Current Microbiology. 62: 331-3. PMID 20625732 DOI: 10.1007/s00284-010-9703-5  0.042
2007 Xu S, Huang X, Xu H, Zhang C. Improved prediction of coreceptor usage and phenotype of HIV-1 based on combined features of V3 loop sequence using random forest. Journal of Microbiology (Seoul, Korea). 45: 441-6. PMID 17978804  0.042
2010 Hu J, Fan H, Liu D, Zhang S, Zhang F, Xu H. DNMT3B promoter polymorphism and risk of gastric cancer. Digestive Diseases and Sciences. 55: 1011-6. PMID 19517237 DOI: 10.1007/s10620-009-0831-3  0.042
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2016 Kong Z, Zhao P, Liu H, Yu X, Qin Y, Su Z, Wang S, Xu H, Chen J. Whole-Genome Sequencing for the Investigation of a Hospital Outbreak of MRSA in China. Plos One. 11: e0149844. PMID 26950298 DOI: 10.1371/journal.pone.0149844  0.039
2008 Zou X, Huang X, Xu S, Zhou L, Sheng X, Zhang H, Xu H, Ezaki T. Identification of a fljA gene on a linear plasmid as the repressor gene of fliC in Salmonella enterica serovar Typhi Microbiology and Immunology. 53: 191-197. DOI: 10.1111/j.1348-0421.2008.00106.x  0.038
2021 Yu Y, Tan P, Zhuang Z, Wang Z, Zhu L, Qiu R, Xu H. Untargeted metabolomic approach to study the serum metabolites in women with polycystic ovary syndrome. Bmc Medical Genomics. 14: 206. PMID 34416878 DOI: 10.1186/s12920-021-01058-y  0.038
2006 Su Z, Xu H, Zhang C, Shao S, Li L, Wang H, Wang H, Qiu G. Mutations in Helicobacter pylori porD and oorD genes may contribute to furazolidone resistance. Croatian Medical Journal. 47: 410-5. PMID 16758519  0.033
2012 Yin Jp, Su Zl, Wang Ym, Wang T, Tian Ss, Xu Xx, Xing Ld, Zhang P, Ma K, Xu Hx. [Release of HMGB1 by LPS-treated cardiac fibroblasts and its contribution to the production of collagen type I and III] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 28: 785-788. PMID 22863579  0.031
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2011 Sandoghchian Shotorbani S, Zhang Y, Baidoo SE, Xu H, Ahmadi M. IL-4 can inhibit IL-17 production in collagen induced arthritis. Iranian Journal of Immunology : Iji. 8: 209-17. PMID 22201618  0.029
2008 Su Z, Dai X, Chen J, Kong F, Wang H, Li Y, Peng S, Wang S, Shao Q, Lv L, Xu H. The bla(CTX-M-1) gene located in a novel complex class I integron bearing an ISCR1 element in Escherichia coli isolates from Zhenjiang, China. The Journal of Antimicrobial Chemotherapy. 62: 1150-1. PMID 18647745 DOI: 10.1093/jac/dkn300  0.028
2009 Chen J, Su Z, Liu Y, Wang S, Dai X, Li Y, Peng S, Shao Q, Zhang H, Wen P, Yu J, Huang X, Xu H. Identification and characterization of class 1 integrons among Pseudomonas aeruginosa isolates from patients in Zhenjiang, China. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 13: 717-21. PMID 19208492 DOI: 10.1016/j.ijid.2008.11.014  0.027
2009 Tong J, Liu C, Summanen PH, Xu H, Finegold SM. Corynebacterium pyruviciproducens sp. nov., a pyruvic acid producer. International Journal of Systematic and Evolutionary Microbiology. 60: 1135-1140. PMID 19666798 DOI: 10.1099/ijs.0.011783-0  0.023
2011 Tong J, Liu C, Summanen P, Xu H, Finegold SM. Application of quantitative real-time PCR for rapid identification of Bacteroides fragilis group and related organisms in human wound samples. Anaerobe. 17: 64-8. PMID 21439390 DOI: 10.1016/j.anaerobe.2011.03.004  0.022
2012 Gong Y, Xu H, Xu Z, Zhang F, Hao C, Gu Y, Lin S, Ding F. Comparison of prognostic value of two kinds of severity scoring systems for hospital mortality prediction of elderly patients with acute kidney injury. Aging Clinical and Experimental Research. 24: 74-8. PMID 21464607 DOI: 10.3275/7624  0.019
2007 Su Z, Xu H, Chen J. Avian influenza: should China be alarmed? Yonsei Medical Journal. 48: 586-94. PMID 17722229 DOI: 10.3349/ymj.2007.48.4.586  0.016
2011 Che LL, Xiao DS, Xu HX, Lu L. Changes of iron stores and duodenal transepithelial iron transfer during regular exercise in rats. Biological Trace Element Research. 143: 1044-53. PMID 21174168 DOI: 10.1007/s12011-010-8919-3  0.013
2013 Su Z, Shotorbani SS, Jiang X, Ma R, Shen H, Kong F, Xu H. A method of experimental rheumatoid arthritis induction using collagen type II isolated from chicken sternal cartilage. Molecular Medicine Reports. 8: 113-7. PMID 23673730 DOI: 10.3892/mmr.2013.1476  0.01
2013 Bu G, Xu H. Reviewer acknowledgement Molecular Neurodegeneration. 8: 11. DOI: 10.1186/1750-1326-8-11  0.01
2012 Gong Y, Xu HX, Lin M, Gu Y. An iatrogenic complication of internal jugular vein catheterization for hemodialysis. Irish Journal of Medical Science. 181: 135-7. PMID 21290197 DOI: 10.1007/s11845-011-0694-4  0.01
2012 Lau J, Hao C, Xu H, Gu J, Wang Z. Syphilis and HIV: Problem and prevention International Journal of Infectious Diseases. 16: e62. DOI: 10.1016/J.Ijid.2012.05.154  0.01
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