319 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines. Acta Neuropathologica. PMID 30690664 DOI: 10.1007/s00401-019-01959-4  0.56
2018 Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. A long-lived aβ oligomer resistant to fibrillization. Biopolymers. PMID 29319162 DOI: 10.1002/bip.23096  0.48
2018 Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, ... ... Prusiner SB, et al. Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311311 DOI: 10.1073/pnas.1714966115  0.96
2017 Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279394 DOI: 10.1073/pnas.1719369115  0.56
2017 Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29203673 DOI: 10.1073/pnas.1717193114  0.56
2017 Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. A novel vector for transgenesis in the rat CNS. Acta Neuropathologica Communications. 5: 84. PMID 29157304 DOI: 10.1186/s40478-017-0484-y  0.56
2017 Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. Jama Neurology. PMID 29059326 DOI: 10.1001/jamaneurol.2017.2822  0.56
2017 Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB. MSA prions exhibit remarkable stability and resistance to inactivation. Acta Neuropathologica. PMID 28849371 DOI: 10.1007/s00401-017-1762-2  0.56
2017 Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, ... Prusiner SB, et al. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nature Chemistry. 9: 874-881. PMID 28837163 DOI: 10.1038/nchem.2754  0.48
2017 Giles K, Woerman AL, Berry DB, Prusiner SB. Bioassays and Inactivation of Prions. Cold Spring Harbor Perspectives in Biology. PMID 28246183 DOI: 10.1101/cshperspect.a023499  0.56
2017 Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB. α-Synuclein: Multiple System Atrophy Prions. Cold Spring Harbor Perspectives in Medicine. PMID 28213437 DOI: 10.1101/cshperspect.a024588  0.96
2017 Watts JC, Prusiner SB. β-Amyloid Prions and the Pathobiology of Alzheimer's Disease. Cold Spring Harbor Perspectives in Medicine. PMID 28193770 DOI: 10.1101/cshperspect.a023507  0.96
2017 Watts JC, Prusiner SB. Experimental Models of Inherited PrP Prion Diseases. Cold Spring Harbor Perspectives in Medicine. PMID 28096244 DOI: 10.1101/cshperspect.a027151  0.96
2017 Giles K, Olson SH, Prusiner SB. Developing Therapeutics for PrP Prion Diseases. Cold Spring Harbor Perspectives in Medicine. PMID 28096242 DOI: 10.1101/cshperspect.a023747  0.56
2016 Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911827 DOI: 10.1073/pnas.1616344113  0.56
2016 Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. Guinea pig prion protein supports rapid propagation of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease prions. Journal of Virology. PMID 27440899 DOI: 10.1128/JVI.01106-16  0.96
2016 Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stoehr J, Hong M. Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. Journal of the American Chemical Society. PMID 27414264 DOI: 10.1021/jacs.6b03715  0.48
2016 Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathologica. PMID 27350609 DOI: 10.1007/s00401-016-1585-6  0.96
2016 Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Optimization of aryl amides that extend survival in prion-infected mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27317802 DOI: 10.1124/jpet.116.235556  0.92
2015 Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, et al. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 112: E5308-17. PMID 26324905 DOI: 10.1073/pnas.1514475112  0.92
2015 Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophysical Journal. 109: 793-805. PMID 26287631 DOI: 10.1016/j.bpj.2015.06.065  0.92
2015 Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, ... ... Prusiner SB, et al. Propagation of prions causing synucleinopathies in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E4949-58. PMID 26286986 DOI: 10.1073/pnas.1513426112  0.96
2015 Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. The Journal of Pharmacology and Experimental Therapeutics. 355: 2-12. PMID 26224882 DOI: 10.1124/jpet.115.224659  0.92
2015 Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB. Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice. The Journal of Infectious Diseases. 212: S17-25. PMID 26116725 DOI: 10.1093/infdis/jiu656  0.92
2015 Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Annals of Neurology. 78: 540-53. PMID 26094969 DOI: 10.1002/ana.24463  0.92
2015 Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G. Structural studies of truncated forms of the prion protein PrP. Biophysical Journal. 108: 1548-54. PMID 25809267 DOI: 10.1016/j.bpj.2015.01.008  0.92
2015 Levine DJ, Stöhr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR. Mechanism of scrapie prion precipitation with phosphotungstate anions. Acs Chemical Biology. 10: 1269-77. PMID 25695325 DOI: 10.1021/cb5006239  0.92
2014 Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 111: 10323-8. PMID 24982139 DOI: 10.1073/pnas.1408900111  0.92
2014 Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 10329-34. PMID 24982137 DOI: 10.1073/pnas.1408968111  0.92
2014 Watts JC, Prusiner SB. Mouse models for studying the formation and propagation of prions. The Journal of Biological Chemistry. 289: 19841-9. PMID 24860095 DOI: 10.1074/jbc.R114.550707  0.92
2014 Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. Evidence that bank vole PrP is a universal acceptor for prions. Plos Pathogens. 10: e1003990. PMID 24699458 DOI: 10.1371/journal.ppat.1003990  0.92
2014 Silber BM, Gever JR, Rao S, Li Z, Renslo AR, Widjaja K, Wong C, Giles K, Freyman Y, Elepano M, Irwin JJ, Jacobson MP, Prusiner SB. Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells. Bioorganic & Medicinal Chemistry. 22: 1960-72. PMID 24530226 DOI: 10.1016/j.bmc.2014.01.001  0.92
2014 Prusiner SB. Madness and Memory: The Discovery of Prions-A New Biological Principle of Disease Madness and Memory: the Discovery of Prions-a New Biological Principle of Disease. 1-320.  0.92
2013 Prusiner SB. Biology and genetics of prions causing neurodegeneration. Annual Review of Genetics. 47: 601-23. PMID 24274755 DOI: 10.1146/annurev-genet-110711-155524  0.92
2013 Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. Transmission of multiple system atrophy prions to transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 19555-60. PMID 24218576 DOI: 10.1073/pnas.1318268110  0.92
2013 Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB. Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Bioorganic & Medicinal Chemistry. 21: 7999-8012. PMID 24183589 DOI: 10.1016/j.bmc.2013.09.022  0.92
2013 Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. Drug resistance confounding prion therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 110: E4160-9. PMID 24128760 DOI: 10.1073/pnas.1317164110  0.92
2013 Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, ... ... Prusiner SB, et al. Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease. Neurology. 81: 2015-23. PMID 24122181 DOI: 10.1212/WNL.0b013e3182a9f3b4  0.92
2013 Li Z, Rao S, Gever JR, Widjaja K, Prusiner SB, Silber BM. Optimization of Arylamides as Novel, Potent and Brain-penetrant Antiprion Lead Compounds. Acs Medicinal Chemistry Letters. 4: 647-650. PMID 23977416 DOI: 10.1021/ml300454k  0.92
2013 Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. 347: 325-38. PMID 23965382 DOI: 10.1124/jpet.113.205799  0.92
2013 Li Z, Gever J, Rao S, Widjaja K, Prusiner SB, Silber BM. Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds. Acs Medicinal Chemistry Letters. 4: 397-401. PMID 23847718 DOI: 10.1021/ml300472n  0.92
2013 Li Z, Silber BM, Rao S, Gever JR, Bryant C, Gallardo-Godoy A, Dolghih E, Widjaja K, Elepano M, Jacobson MP, Prusiner SB, Renslo AR. 2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease. Chemmedchem. 8: 847-57. PMID 23509039 DOI: 10.1002/cmdc.201300007  0.92
2013 Godsave SF, Wille H, Pierson J, Prusiner SB, Peters PJ. Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo. Neurobiology of Aging. 34: 1621-31. PMID 23481568 DOI: 10.1016/j.neurobiolaging.2012.12.015  0.92
2013 Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Convergent replication of mouse synthetic prion strains. The American Journal of Pathology. 182: 866-74. PMID 23438476 DOI: 10.1016/j.ajpath.2012.11.038  0.92
2013 Silber BM, Rao S, Fife KL, Gallardo-Godoy A, Renslo AR, Dalvie DK, Giles K, Freyman Y, Elepano M, Gever JR, Li Z, Jacobson MP, Huang Y, Benet LZ, Prusiner SB. Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharmaceutical Research. 30: 932-50. PMID 23417511 DOI: 10.1007/s11095-012-0912-4  0.92
2013 Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. Chimeric elk/mouse prion proteins in transgenic mice. The Journal of General Virology. 94: 443-52. PMID 23100369 DOI: 10.1099/vir.0.045989-0  0.92
2012 Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Molecular Therapy. Nucleic Acids. 1: e9. PMID 23344724 DOI: 10.1038/mtna.2011.6  0.92
2012 Stanker LH, Scotcher MC, Lin A, McGarvey J, Prusiner SB, Hnasko R. Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions. Hybridoma (2005). 31: 314-24. PMID 23098297 DOI: 10.1089/hyb.2012.0022  0.92
2012 Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. Plos One. 7: e39112. PMID 22768295 DOI: 10.1371/journal.pone.0039112  0.92
2012 Prusiner SB. Cell biology. A unifying role for prions in neurodegenerative diseases. Science (New York, N.Y.). 336: 1511-3. PMID 22723400 DOI: 10.1126/science.1222951  0.92
2012 Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proceedings of the National Academy of Sciences of the United States of America. 109: 11025-30. PMID 22711819 DOI: 10.1073/pnas.1206555109  0.92
2012 Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G. Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold. Biophysical Journal. 102: 2339-44. PMID 22677387 DOI: 10.1016/j.bpj.2012.04.011  0.92
2012 Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB. Salivary prions in sheep and deer. Prion. 6: 52-61. PMID 22453179 DOI: 10.4161/pri.6.1.16984  0.92
2012 Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL. Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling. Analytical Chemistry. 84: 4014-21. PMID 22444387 DOI: 10.1021/ac203330z  0.92
2012 Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. Identification of I137M and other mutations that modulate incubation periods for two human prion strains. Journal of Virology. 86: 6033-41. PMID 22438549 DOI: 10.1128/JVI.07027-11  0.92
2012 Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 3498-503. PMID 22331873 DOI: 10.1073/pnas.1121556109  0.92
2011 Kujala P, Raymond CR, Romeijn M, Godsave SF, van Kasteren SI, Wille H, Prusiner SB, Mabbott NA, Peters PJ. Prion uptake in the gut: identification of the first uptake and replication sites. Plos Pathogens. 7: e1002449. PMID 22216002 DOI: 10.1371/journal.ppat.1002449  0.92
2011 Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. Protease-resistant prions selectively decrease Shadoo protein. Plos Pathogens. 7: e1002382. PMID 22163178 DOI: 10.1371/journal.ppat.1002382  0.92
2011 Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. Spontaneous generation of anchorless prions in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 21223-8. PMID 22160704 DOI: 10.1073/pnas.1117827108  0.92
2011 Colby DW, Prusiner SB. De novo generation of prion strains. Nature Reviews. Microbiology. 9: 771-7. PMID 21947062 DOI: 10.1038/nrmicro2650  0.92
2011 Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL. A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Molecular & Cellular Proteomics : McP. 10: M111.010728. PMID 21937731 DOI: 10.1074/mcp.M111.010728  0.92
2011 Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. Conformational transformation and selection of synthetic prion strains. Journal of Molecular Biology. 413: 527-42. PMID 21839745 DOI: 10.1016/j.jmb.2011.07.021  0.92
2011 Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. Conserved properties of human and bovine prion strains on transmission to guinea pigs. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1326-36. PMID 21727894 DOI: 10.1038/labinvest.2011.89  0.92
2011 Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S. A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets. The Journal of Biological Chemistry. 286: 27718-28. PMID 21610081 DOI: 10.1074/jbc.M111.234393  0.92
2011 Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 2528-33. PMID 21262831 DOI: 10.1073/pnas.1019034108  0.92
2011 Gallardo-Godoy A, Gever J, Fife KL, Silber BM, Prusiner SB, Renslo AR. 2-Aminothiazoles as therapeutic leads for prion diseases. Journal of Medicinal Chemistry. 54: 1010-21. PMID 21247166 DOI: 10.1021/jm101250y  0.92
2010 Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 14508-13. PMID 20699386 DOI: 10.1073/pnas.1006551107  0.92
2010 Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. Human prion strain selection in transgenic mice. Annals of Neurology. 68: 151-61. PMID 20695008 DOI: 10.1002/ana.22104  0.92
2010 Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH. Generation of antisera to purified prions in lipid rafts. Prion. 4: 94-104. PMID 20647769 DOI: 10.4161/pri.4.2.12622  0.92
2010 Stanker LH, Serban AV, Cleveland E, Hnasko R, Lemus A, Safar J, DeArmond SJ, Prusiner SB. Conformation-dependent high-affinity monoclonal antibodies to prion proteins. Journal of Immunology (Baltimore, Md. : 1950). 185: 729-37. PMID 20530267 DOI: 10.4049/jimmunol.0902930  0.92
2010 Doak AK, Wille H, Prusiner SB, Shoichet BK. Colloid formation by drugs in simulated intestinal fluid. Journal of Medicinal Chemistry. 53: 4259-65. PMID 20426472 DOI: 10.1021/jm100254w  0.92
2010 Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, Lemus A, Cohen FE, DeArmond SJ, Prusiner SB. Protease-sensitive synthetic prions. Plos Pathogens. 6: e1000736. PMID 20107515 DOI: 10.1371/journal.ppat.1000736  0.92
2010 Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of Virology. 84: 3408-12. PMID 20032192 DOI: 10.1128/JVI.02145-09  0.92
2010 Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB. Chemical induction of misfolded prion protein conformers in cell culture. The Journal of Biological Chemistry. 285: 10415-23. PMID 19955177 DOI: 10.1074/jbc.M109.045112  0.92
2009 Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. Continuous quinacrine treatment results in the formation of drug-resistant prions. Plos Pathogens. 5: e1000673. PMID 19956709 DOI: 10.1371/journal.ppat.1000673  0.92
2009 Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB. Design and construction of diverse mammalian prion strains. Proceedings of the National Academy of Sciences of the United States of America. 106: 20417-22. PMID 19915150 DOI: 10.1073/pnas.0910350106  0.92
2009 Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G. Natural and synthetic prion structure from X-ray fiber diffraction. Proceedings of the National Academy of Sciences of the United States of America. 106: 16990-5. PMID 19805070 DOI: 10.1073/pnas.0909006106  0.92
2009 Tamgüney G, Miller MW, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB. Asymptomatic deer excrete infectious prions in faeces. Nature. 461: 529-32. PMID 19741608 DOI: 10.1038/nature08289  0.92
2009 Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. Measuring prions by bioluminescence imaging. Proceedings of the National Academy of Sciences of the United States of America. 106: 15002-6. PMID 19706444 DOI: 10.1073/pnas.0907339106  0.92
2009 Olanow CW, Prusiner SB. Is Parkinson's disease a prion disorder? Proceedings of the National Academy of Sciences of the United States of America. 106: 12571-2. PMID 19666621 DOI: 10.1073/pnas.0906759106  0.92
2009 Bae SH, Legname G, Serban A, Prusiner SB, Wright PE, Dyson HJ. Prion proteins with pathogenic and protective mutations show similar structure and dynamics. Biochemistry. 48: 8120-8. PMID 19618915 DOI: 10.1021/bi900923b  0.92
2009 Choi EM, Geschwind MD, Deering C, Pomeroy K, Kuo A, Miller BL, Safar JG, Prusiner SB. Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 624-35. PMID 19434060 DOI: 10.1038/labinvest.2009.30  0.92
2009 Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB. Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein. The Journal of General Virology. 90: 1035-47. PMID 19264659 DOI: 10.1099/vir.0.007500-0  0.92
2009 Campana V, Zentilin L, Mirabile I, Kranjc A, Casanova P, Giacca M, Prusiner SB, Legname G, Zurzolo C. Development of antibody fragments for immunotherapy of prion diseases. The Biochemical Journal. 418: 507-15. PMID 19000036 DOI: 10.1042/BJ20081541  0.92
2008 Godsave SF, Wille H, Kujala P, Latawiec D, DeArmond SJ, Serban A, Prusiner SB, Peters PJ. Cryo-immunogold electron microscopy for prions: toward identification of a conversion site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12489-99. PMID 19020041 DOI: 10.1523/JNEUROSCI.4474-08.2008  0.92
2008 Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB. Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. Plos Pathogens. 4: e1000206. PMID 19008948 DOI: 10.1371/journal.ppat.1000206  0.92
2008 Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proceedings of the National Academy of Sciences of the United States of America. 105: 10595-600. PMID 18647832 DOI: 10.1073/pnas.0803671105  0.92
2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Prusiner SB, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/vir.0.2008/001255-0  0.92
2008 Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, Dearmond SJ, Prusiner SB. Transmission and detection of prions in feces. The Journal of Infectious Diseases. 198: 81-9. PMID 18505383 DOI: 10.1086/588193  0.92
2008 Stöhr J, Weinmann N, Wille H, Kaimann T, Nagel-Steger L, Birkmann E, Panza G, Prusiner SB, Eigen M, Riesner D. Mechanisms of prion protein assembly into amyloid. Proceedings of the National Academy of Sciences of the United States of America. 105: 2409-14. PMID 18268326 DOI: 10.1073/pnas.0712036105  0.92
2008 Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Small-molecule aggregates inhibit amyloid polymerization. Nature Chemical Biology. 4: 197-9. PMID 18223646 DOI: 10.1038/nchembio.65  0.92
2008 Prusiner SB. Reflections on kuru Philosophical Transactions of the Royal Society B: Biological Sciences. 363: 3654-3656. DOI: 10.1098/rstb.2008.4024  0.92
2008 Colby DW, Zhang Q, Wang S, Groth D, Legname G, Riesner D, Prusiner SB. Prion detection by an amyloid seeding assay (Proceedings of the National Academy of Sciences of the United States of America (December 26, 2007) 104, 52, (20914-20919) DOI:10.1073/pnas.0710152105) Proceedings of the National Academy of Sciences of the United States of America. 105: 1774. DOI: 10.1073/pnas.0712052105  0.92
2007 Colby DW, Zhang Q, Wang S, Groth D, Legname G, Riesner D, Prusiner SB. Prion detection by an amyloid seeding assay. Proceedings of the National Academy of Sciences of the United States of America. 104: 20914-9. PMID 18096717 DOI: 10.1073/pnas.0710152105  0.92
2007 Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB. Cell division modulates prion accumulation in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 17971-6. PMID 17989223 DOI: 10.1073/pnas.0708372104  0.92
2007 Wille H, Govaerts C, Borovinskiy A, Latawiec D, Downing KH, Cohen FE, Prusiner SB. Electron crystallography of the scrapie prion protein complexed with heavy metals. Archives of Biochemistry and Biophysics. 467: 239-48. PMID 17935686 DOI: 10.1016/j.abb.2007.08.010  0.92
2007 Müller H, Stitz L, Wille H, Prusiner SB, Riesner D. Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation. The Journal of Biological Chemistry. 282: 35855-67. PMID 17878157 DOI: 10.1074/jbc.M706883200  0.92
2007 Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Molecular Medicine (Cambridge, Mass.). 13: 190-8. PMID 17592554 DOI: 10.2119/2006–00073.Karpuj  0.92
2007 King DJ, Safar JG, Legname G, Prusiner SB. Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites. Journal of Molecular Biology. 369: 1001-14. PMID 17481659 DOI: 10.1016/j.jmb.2007.02.004  0.92
2007 Norrby E, Prusiner SB. Polio and Nobel prizes: looking back 50 years. Annals of Neurology. 61: 385-95. PMID 17469121 DOI: 10.1002/ana.21153  0.92
2007 Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BC. Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds. The Journal of General Virology. 88: 1392-401. PMID 17374787 DOI: 10.1099/vir.0.82601-0  0.92
2007 Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M, Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB. Transgenic mouse brains for the evaluation and quality control of BSE tests. Biological Chemistry. 388: 349-54. PMID 17338644 DOI: 10.1515/BC.2007.040  0.92
2007 Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ. Developmental expression of PrP in the post-implantation embryo. Brain Research. 1139: 60-7. PMID 17292334 DOI: 10.1016/j.brainres.2006.12.055  0.92
2007 May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE. Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics. Journal of Medicinal Chemistry. 50: 65-73. PMID 17201410 DOI: 10.1021/jm061045z  0.92
2007 Diez M, Groth D, DeArmond SJ, Prusiner SB, Hökfelt T. Changes in neuropeptide expression in mice infected with prions. Neurobiology of Aging. 28: 748-65. PMID 16621165 DOI: 10.1016/j.neurobiolaging.2006.02.017  0.92
2007 Giles K, Supattapone S, Peretz D, Glidden DV, Baron H, Prusiner SB. Disinfection of prions Acs Symposium Series. 967: 52-74.  0.92
2006 Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 103: 19105-10. PMID 17142317 DOI: 10.1073/pnas.0608970103  0.92
2006 Prusiner SB, McCarty M. Discovering DNA encodes heredity and prions are infectious proteins. Annual Review of Genetics. 40: 25-45. PMID 17094736 DOI: 10.1146/annurev.genet.40.121505.133522  0.92
2006 Luginbühl B, Kanyo Z, Jones RM, Fletterick RJ, Prusiner SB, Cohen FE, Williamson RA, Burton DR, Plückthun A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. Journal of Molecular Biology. 363: 75-97. PMID 16962610 DOI: 10.1016/j.jmb.2006.07.027  0.92
2006 Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB. Transmission of elk and deer prions to transgenic mice. Journal of Virology. 80: 9104-14. PMID 16940522 DOI: 10.1128/JVI.00098-06  0.92
2006 Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG. Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models. Neuroimage. 33: 449-62. PMID 16931059 DOI: 10.1016/j.neuroimage.2006.05.055  0.92
2006 May BC, Witkop J, Sherrill J, Anderson MO, Madrid PB, Zorn JA, Prusiner SB, Cohen FE, Guy RK. Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells. Bioorganic & Medicinal Chemistry Letters. 16: 4913-6. PMID 16860557 DOI: 10.1016/j.bmcl.2006.06.050  0.92
2006 Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB. Human prions and plasma lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 11312-7. PMID 16849426 DOI: 10.1073/pnas.0604021103  0.92
2006 Leclerc E, Serban H, Prusiner SB, Burton DR, Williamson RA. Copper induces conformational changes in the N-terminal part of cell-surface PrPC. Archives of Virology. 151: 2103-9. PMID 16791441 DOI: 10.1007/s00705-006-0804-1  0.92
2006 Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET. Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1136-44. PMID 16581945 DOI: 10.1124/dmd.105.008664  0.92
2006 Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson GA. Prion infection of mouse neurospheres. Proceedings of the National Academy of Sciences of the United States of America. 103: 3875-80. PMID 16495413 DOI: 10.1073/pnas.0510902103  0.92
2006 Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB. Inactivation of prions by acidic sodium dodecyl sulfate. Journal of Virology. 80: 322-31. PMID 16352557 DOI: 10.1128/JVI.80.1.322-331.2006  0.92
2006 Lim KH, Nguyen TN, Damo SM, Mazur T, Ball HL, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nuclear Magnetic Resonance. 29: 183-90. PMID 16256316 DOI: 10.1016/j.ssnmr.2005.09.017  0.92
2006 Prusiner SB. History of prion research Prions in Humans and Animals. 44-57. DOI: 10.1515/9783110200171  0.92
2005 Kanaani J, Prusiner SB, Diacovo J, Baekkeskov S, Legname G. Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro. Journal of Neurochemistry. 95: 1373-86. PMID 16313516 DOI: 10.1111/j.1471-4159.2005.03469.x  0.92
2005 Lee IS, Long JR, Prusiner SB, Safar JG. Selective precipitation of prions by polyoxometalate complexes. Journal of the American Chemical Society. 127: 13802-3. PMID 16201796 DOI: 10.1021/ja055219y  0.92
2005 Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P. Prion clearance in bigenic mice. The Journal of General Virology. 86: 2913-23. PMID 16186247 DOI: 10.1099/vir.0.80947-0  0.92
2005 Safar JG, Kellings K, Serban A, Groth D, Cleaver JE, Prusiner SB, Riesner D. Search for a prion-specific nucleic acid. Journal of Virology. 79: 10796-806. PMID 16051871 DOI: 10.1128/JVI.79.16.10796-10806.2005  0.92
2005 Leffers KW, Wille H, Stöhr J, Junger E, Prusiner SB, Riesner D. Assembly of natural and recombinant prion protein into fibrils. Biological Chemistry. 386: 569-80. PMID 16006244 DOI: 10.1515/BC.2005.067  0.92
2005 Scott MR, Peretz D, Nguyen HO, Dearmond SJ, Prusiner SB. Transmission barriers for bovine, ovine, and human prions in transgenic mice. Journal of Virology. 79: 5259-71. PMID 15827140 DOI: 10.1128/JVI.79.9.5259-5271.2005  0.92
2005 Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. Diagnosis of human prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 3501-6. PMID 15741275 DOI: 10.1073/pnas.0409651102  0.92
2005 Legname G, Nguyen HO, Baskakov IV, Cohen FE, Dearmond SJ, Prusiner SB. Strain-specified characteristics of mouse synthetic prions. Proceedings of the National Academy of Sciences of the United States of America. 102: 2168-73. PMID 15671162 DOI: 10.1073/pnas.0409079102  0.92
2005 Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ. Notch-1 activation and dendritic atrophy in prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 886-91. PMID 15640354 DOI: 10.1073/pnas.0408612101  0.92
2005 Prusiner SB. Remembering Radoslav Andjus Annals of the New York Academy of Sciences. 1048: 1-4. DOI: 10.1196/annals.1342.000  0.92
2004 Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ. Pharmacokinetics of quinacrine in the treatment of prion disease. Bmc Infectious Diseases. 4: 53. PMID 15569390 DOI: 10.1186/1471-2334-4-53  0.92
2004 Requena JR, Dimitrova MN, Legname G, Teijeira S, Prusiner SB, Levine RL. Oxidation of methionine residues in the prion protein by hydrogen peroxide. Archives of Biochemistry and Biophysics. 432: 188-95. PMID 15542057 DOI: 10.1016/j.abb.2004.09.012  0.92
2004 Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ, DeArmond SJ. The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system. Journal of Neuropathology and Experimental Neurology. 63: 882-99. PMID 15330342  0.92
2004 Serban A, Legname G, Hansen K, Kovaleva N, Prusiner SB. Immunoglobulins in urine of hamsters with scrapie. The Journal of Biological Chemistry. 279: 48817-20. PMID 15310752 DOI: 10.1074/jbc.M409107200  0.92
2004 Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB. Synthetic mammalian prions. Science (New York, N.Y.). 305: 673-6. PMID 15286374 DOI: 10.1126/science.1100195  0.92
2004 Prusiner SB. Detecting mad cow disease. Scientific American. 291: 86-93. PMID 15255592  0.92
2004 Govaerts C, Wille H, Prusiner SB, Cohen FE. Evidence for assembly of prions with left-handed beta-helices into trimers. Proceedings of the National Academy of Sciences of the United States of America. 101: 8342-7. PMID 15155909 DOI: 10.1073/pnas.0402254101  0.92
2004 Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nature Biotechnology. 22: 724-31. PMID 15146195 DOI: 10.1038/nbt969  0.92
2004 May BC, Govaerts C, Prusiner SB, Cohen FE. Prions: so many fibers, so little infectivity. Trends in Biochemical Sciences. 29: 162-5. PMID 15124628 DOI: 10.1016/j.tibs.2004.02.008  0.92
2004 Prusiner SB. Early evidence that a protease-resistant protein is an active component of the infectious prion. Cell. 116: S109, 1 p following . PMID 15055596  0.92
2004 Goldman JS, Miller BL, Safar J, de Tourreil S, Martindale JL, Prusiner SB, Geschwind MD. When sporadic disease is not sporadic: the potential for genetic etiology. Archives of Neurology. 61: 213-6. PMID 14967768 DOI: 10.1001/archneur.61.2.213  0.92
2004 Baskakov IV, Legname G, Gryczynski Z, Prusiner SB. The peculiar nature of unfolding of the human prion protein. Protein Science : a Publication of the Protein Society. 13: 586-95. PMID 14767078 DOI: 10.1110/ps.03457204  0.92
2004 Tremblay P, Ball HL, Kaneko K, Groth D, Hegde RS, Cohen FE, DeArmond SJ, Prusiner SB, Safar JG. Mutant PrPSc conformers induced by a synthetic peptide and several prion strains. Journal of Virology. 78: 2088-99. PMID 14747574 DOI: 10.1128/JVI.78.4.2088-2099.2004  0.92
2003 Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB. Trafficking of prion proteins through a caveolae-mediated endosomal pathway. The Journal of Cell Biology. 162: 703-17. PMID 12925711 DOI: 10.1083/jcb.200304140  0.92
2003 Mironov A, Latawiec D, Wille H, Bouzamondo-Bernstein E, Legname G, Williamson RA, Burton D, DeArmond SJ, Prusiner SB, Peters PJ. Cytosolic prion protein in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7183-93. PMID 12904479  0.92
2003 Ryou C, Legname G, Peretz D, Craig JC, Baldwin MA, Prusiner SB. Differential inhibition of prion propagation by enantiomers of quinacrine. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 837-43. PMID 12808118  0.92
2003 Burns CS, Aronoff-Spencer E, Legname G, Prusiner SB, Antholine WE, Gerfen GJ, Peisach J, Millhauser GL. Copper coordination in the full-length, recombinant prion protein. Biochemistry. 42: 6794-803. PMID 12779334 DOI: 10.1021/bi027138+  0.92
2003 Ryou C, Prusiner SB, Legname G. Cooperative binding of dominant-negative prion protein to kringle domains. Journal of Molecular Biology. 329: 323-33. PMID 12758079 DOI: 10.1016/S0022-2836(03)00342-5  0.92
2003 DeArmond SJ, Prusiner SB. Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. Clinics in Laboratory Medicine. 23: 1-41. PMID 12733423 DOI: 10.1016/S0272-2712(02)00041-0  0.92
2003 Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proceedings of the National Academy of Sciences of the United States of America. 100: 4784-9. PMID 12684540 DOI: 10.1073/pnas.2627989100  0.92
2003 May BC, Fafarman AT, Hong SB, Rogers M, Deady LW, Prusiner SB, Cohen FE. Potent inhibition of scrapie prion replication in cultured cells by bis-acridines. Proceedings of the National Academy of Sciences of the United States of America. 100: 3416-21. PMID 12626750 DOI: 10.1073/pnas.2627988100  0.92
2003 Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA. Conformation of PrP(C) on the cell surface as probed by antibodies. Journal of Molecular Biology. 326: 475-83. PMID 12559915 DOI: 10.1016/S0022-2836(02)01365-7  0.92
2003 Qin K, Coomaraswamy J, Mastrangelo P, Yang Y, Lugowski S, Petromilli C, Prusiner SB, Fraser PE, Goldberg JM, Chakrabartty A, Westaway D. The PrP-like protein Doppel binds copper. The Journal of Biological Chemistry. 278: 8888-96. PMID 12482851 DOI: 10.1074/jbc.M210875200  0.92
2002 Prusiner SB. Historical essay. Discovering the cause of AIDS. Science (New York, N.Y.). 298: 1726. PMID 12459574 DOI: 10.1126/science.1079874  0.92
2002 Legname G, Nelken P, Guan Z, Kanyo ZF, DeArmond SJ, Prusiner SB. Prion and doppel proteins bind to granule cells of the cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 99: 16285-90. PMID 12446843 DOI: 10.1073/pnas.242611999  0.92
2002 Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA. Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nature Biotechnology. 20: 1147-50. PMID 12389035 DOI: 10.1038/nbt748  0.92
2002 Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James TL. Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry. 41: 12277-83. PMID 12369815 DOI: 10.1021/bi026129y  0.92
2002 Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. Dominant-negative inhibition of prion replication in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 13079-84. PMID 12271119 DOI: 10.1073/pnas.182425299  0.92
2002 Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR. A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron. 34: 921-32. PMID 12086640 DOI: 10.1016/S0896-6273(02)00726-2  0.92
2002 Baskakov IV, Legname G, Baldwin MA, Prusiner SB, Cohen FE. Pathway complexity of prion protein assembly into amyloid. The Journal of Biological Chemistry. 277: 21140-8. PMID 11912192 DOI: 10.1074/jbc.M111402200  0.92
2002 Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. Prions in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 3812-7. PMID 11904434 DOI: 10.1073/pnas.052707499  0.92
2002 Wille H, Michelitsch MD, Guenebaut V, Supattapone S, Serban A, Cohen FE, Agard DA, Prusiner SB. Structural studies of the scrapie prion protein by electron crystallography. Proceedings of the National Academy of Sciences of the United States of America. 99: 3563-8. PMID 11891310 DOI: 10.1073/pnas.052703499  0.92
2002 Nicholson EM, Mo H, Prusiner SB, Cohen FE, Marqusee S. Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation. Journal of Molecular Biology. 316: 807-15. PMID 11866533 DOI: 10.1006/jmbi.2001.5347  0.92
2001 Ball HL, King DS, Cohen FE, Prusiner SB, Baldwin MA. Engineering the prion protein using chemical synthesis. The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 357-74. PMID 11892845 DOI: 10.1034/j.1399-3011.2001.00943.x  0.92
2001 Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, Prusiner SB, DeArmond SJ. Inherited prion disease caused by the V210I mutation: transmission to transgenic mice. Neurology. 57: 2198-205. PMID 11756597  0.92
2001 Schmitt-Ulms G, Legname G, Baldwin MA, Ball HL, Bradon N, Bosque PJ, Crossin KL, Edelman GM, DeArmond SJ, Cohen FE, Prusiner SB. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. Journal of Molecular Biology. 314: 1209-25. PMID 11743735 DOI: 10.1006/jmbi.2000.5183  0.92
2001 Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P. Doppel-induced cerebellar degeneration in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 15288-93. PMID 11734625 DOI: 10.1073/pnas.251550798  0.92
2001 Moore RC, Xiang F, Monaghan J, Han D, Zhang Z, Edström L, Anvret M, Prusiner SB. Huntington disease phenocopy is a familial prion disease. American Journal of Human Genetics. 69: 1385-8. PMID 11593450 DOI: 10.1086/324414  0.92
2001 Schlumpberger M, Prusiner SB, Herskowitz I. Induction of distinct [URE3] yeast prion strains. Molecular and Cellular Biology. 21: 7035-46. PMID 11564886 DOI: 10.1128/MCB.21.20.7035-7046.2001  0.92
2001 Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille H, Cohen FE, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 98: 11686-90. PMID 11562491 DOI: 10.1073/pnas.201404298  0.92
2001 Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature. 412: 739-43. PMID 11507642 DOI: 10.1038/35089090  0.92
2001 Korth C, May BC, Cohen FE, Prusiner SB. Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 9836-41. PMID 11504948 DOI: 10.1073/pnas.161274798  0.92
2001 Diez M, DeArmond SJ, Groth D, Prusiner SB, Hökfelt T. Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice. Neurobiology of Disease. 8: 692-9. PMID 11493033 DOI: 10.1006/nbdi.2001.0404  0.92
2001 Jansen K, Schäfer O, Birkmann E, Post K, Serban H, Prusiner SB, Riesner D. Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form. Biological Chemistry. 382: 683-91. PMID 11405232 DOI: 10.1515/BC.2001.081  0.92
2001 Requena JR, Groth D, Legname G, Stadtman ER, Prusiner SB, Levine RL. Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 7170-5. PMID 11404462 DOI: 10.1073/pnas.121190898  0.92
2001 Matsunaga Y, Peretz D, Williamson A, Burton D, Mehlhorn I, Groth D, Cohen FE, Prusiner SB, Baldwin MA. Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH. Proteins. 44: 110-8. PMID 11391773 DOI: 10.1002/prot.1077  0.92
2001 Prusiner SB. Shattuck lecture--neurodegenerative diseases and prions. The New England Journal of Medicine. 344: 1516-26. PMID 11357156 DOI: 10.1056/NEJM200105173442006  0.92
2001 Baskakov IV, Legname G, Prusiner SB, Cohen FE. Folding of prion protein to its native alpha-helical conformation is under kinetic control. The Journal of Biological Chemistry. 276: 19687-90. PMID 11306559 DOI: 10.1074/jbc.C100180200  0.92
2001 Rudd PM, Wormald MR, Wing DR, Prusiner SB, Dwek RA. Prion glycoprotein: structure, dynamics, and roles for the sugars. Biochemistry. 40: 3759-66. PMID 11300755 DOI: 10.1021/bi002625f  0.92
2001 Leclerc E, Peretz D, Ball H, Sakurai H, Legname G, Serban A, Prusiner SB, Burton DR, Williamson RA. Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form. The Embo Journal. 20: 1547-54. PMID 11285219 DOI: 10.1093/emboj/20.7.1547  0.92
2001 Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB. Strain-specified relative conformational stability of the scrapie prion protein. Protein Science : a Publication of the Protein Society. 10: 854-63. PMID 11274476 DOI: 10.1110/ps.39201  0.92
2001 Harrison PM, Chan HS, Prusiner SB, Cohen FE. Conformational propagation with prion-like characteristics in a simple model of protein folding. Protein Science : a Publication of the Protein Society. 10: 819-35. PMID 11274473 DOI: 10.1110/ps.38701  0.92
2001 Supattapone S, Bouzamondo E, Ball HL, Wille H, Nguyen HO, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice. Molecular and Cellular Biology. 21: 2608-16. PMID 11259607 DOI: 10.1128/MCB.21.7.2608-2616.2001  0.92
2001 Viles JH, Donne D, Kroon G, Prusiner SB, Cohen FE, Dyson HJ, Wright PE. Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics. Biochemistry. 40: 2743-53. PMID 11258885 DOI: 10.1021/bi002898a  0.92
2001 Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. Branched polyamines cure prion-infected neuroblastoma cells. Journal of Virology. 75: 3453-61. PMID 11238871 DOI: 10.1128/JVI.75.7.3453-3461.2001  0.92
2001 Mo H, Moore RC, Cohen FE, Westaway D, Prusiner SB, Wright PE, Dyson HJ. Two different neurodegenerative diseases caused by proteins with similar structures. Proceedings of the National Academy of Sciences of the United States of America. 98: 2352-7. PMID 11226243 DOI: 10.1073/pnas.051627998  0.92
2001 Supattapone S, Muramoto T, Legname G, Mehlhorn I, Cohen FE, DeArmond SJ, Prusiner SB, Scott MR. Identification of two prion protein regions that modify scrapie incubation time. Journal of Virology. 75: 1408-13. PMID 11152514 DOI: 10.1128/JVI.75.3.1408-1413.2001  0.92
2000 Safar J, Cohen FE, Prusiner SB. Quantitative traits of prion strains are enciphered in the conformation of the prion protein. Archives of Virology. Supplementum. 227-35. PMID 11214926  0.92
2000 Scott MR, Supattapone S, Nguyen HO, DeArmond SJ, Prusiner SB. Transgenic models of prion disease. Archives of Virology. Supplementum. 113-24. PMID 11214913  0.92
2000 Supattapone S, Nguyen HO, Muramoto T, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations. Journal of Virology. 74: 11928-34. PMID 11090193 DOI: 10.1128/JVI.74.24.11928-11934.2000  0.92
2000 Aronoff-Spencer E, Burns CS, Avdievich NI, Gerfen GJ, Peisach J, Antholine WE, Ball HL, Cohen FE, Prusiner SB, Millhauser GL. Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy. Biochemistry. 39: 13760-71. PMID 11076515 DOI: 10.1021/bi001472t  0.92
2000 Stephenson DA, Chiotti K, Ebeling C, Groth D, DeArmond SJ, Prusiner SB, Carlson GA. Quantitative trait loci affecting prion incubation time in mice. Genomics. 69: 47-53. PMID 11013074 DOI: 10.1006/geno.2000.6320  0.92
2000 Korth C, Kaneko K, Prusiner SB. Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains. The Journal of General Virology. 81: 2555-63. PMID 10993946  0.92
2000 Bouzamondo E, Milroy AM, Ralston HJ, Prusiner SB, DeArmond SJ. Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation. Brain Research. 874: 210-5. PMID 10960606  0.92
2000 Wille H, Prusiner SB, Cohen FE. Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein. Journal of Structural Biology. 130: 323-38. PMID 10940236 DOI: 10.1006/jsbi.2000.4242  0.92
2000 Inouye H, Bond J, Baldwin MA, Ball HL, Prusiner SB, Kirschner DA. Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions. Journal of Molecular Biology. 300: 1283-96. PMID 10903869 DOI: 10.1006/jmbi.2000.3926  0.92
2000 Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D. Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss. The Journal of Biological Chemistry. 275: 26834-41. PMID 10842180 DOI: 10.1074/jbc.M003888200  0.92
2000 Perrier V, Wallace AC, Kaneko K, Safar J, Prusiner SB, Cohen FE. Mimicking dominant negative inhibition of prion replication through structure-based drug design. Proceedings of the National Academy of Sciences of the United States of America. 97: 6073-8. PMID 10823951 DOI: 10.1073/pnas.97.11.6073  0.92
2000 Bosque PJ, Prusiner SB. Cultured cell sublines highly susceptible to prion infection. Journal of Virology. 74: 4377-86. PMID 10756052 DOI: 10.1128/JVI.74.9.4377-4386.2000  0.92
2000 Zulianello L, Kaneko K, Scott M, Erpel S, Han D, Cohen FE, Prusiner SB. Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein. Journal of Virology. 74: 4351-60. PMID 10756050 DOI: 10.1128/JVI.74.9.4351-4360.2000  0.92
2000 Schlumpberger M, Wille H, Baldwin MA, Butler DA, Herskowitz I, Prusiner SB. The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein. Protein Science : a Publication of the Protein Society. 9: 440-51. PMID 10752606 DOI: 10.1110/ps.9.3.440  0.92
2000 Whittal RM, Ball HL, Cohen FE, Burlingame AL, Prusiner SB, Baldwin MA. Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Science : a Publication of the Protein Society. 9: 332-43. PMID 10716185 DOI: 10.1110/ps.9.2.332  0.92
2000 Baskakov IV, Aagaard C, Mehlhorn I, Wille H, Groth D, Baldwin MA, Prusiner SB, Cohen FE. Self-assembly of recombinant prion protein of 106 residues. Biochemistry. 39: 2792-804. PMID 10704232 DOI: 10.1021/bi9923353  0.92
2000 Kaneko K, Ball HL, Wille H, Zhang H, Groth D, Torchia M, Tremblay P, Safar J, Prusiner SB, DeArmond SJ, Baldwin MA, Cohen FE. A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice. Journal of Molecular Biology. 295: 997-1007. PMID 10656806 DOI: 10.1006/jmbi.1999.3386  0.92
1999 Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR. Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature. 402: 822-6. PMID 10617204 DOI: 10.1038/45574  0.92
1999 Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proceedings of the National Academy of Sciences of the United States of America. 96: 15137-42. PMID 10611351 DOI: 10.1073/pnas.96.26.15137  0.92
1999 Tatzelt J, Groth DF, Torchia M, Prusiner SB, DeArmond SJ. Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie. Journal of Neuropathology and Experimental Neurology. 58: 1244-9. PMID 10604749  0.64
1999 Supattapone S, Nguyen HO, Cohen FE, Prusiner SB, Scott MR. Elimination of prions by branched polyamines and implications for therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 96: 14529-34. PMID 10588739 DOI: 10.1073/pnas.96.25.14529  0.92
1999 Rudd PM, Endo T, Colominas C, Groth D, Wheeler SF, Harvey DJ, Wormald MR, Serban H, Prusiner SB, Kobata A, Dwek RA. Glycosylation differences between the normal and pathogenic prion protein isoforms. Proceedings of the National Academy of Sciences of the United States of America. 96: 13044-9. PMID 10557270  0.4
1999 Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE. Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. Journal of Molecular Biology. 293: 855-63. PMID 10543972 DOI: 10.1006/jmbi.1999.3193  0.92
1999 Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, ... ... Prusiner SB, et al. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. Journal of Molecular Biology. 292: 797-817. PMID 10525406 DOI: 10.1006/jmbi.1999.3108  0.92
1999 Nishida N, Tremblay P, Sugimoto T, Shigematsu K, Shirabe S, Petromilli C, Erpel SP, Nakaoke R, Atarashi R, Houtani T, Torchia M, Sakaguchi S, DeArmond SJ, Prusiner SB, Katamine S. A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 689-97. PMID 10378511  0.64
1999 Mastrianni JA, Nixon R, Layzer R, Telling GC, Han D, DeArmond SJ, Prusiner SB. Prion protein conformation in a patient with sporadic fatal insomnia. The New England Journal of Medicine. 340: 1630-8. PMID 10341275 DOI: 10.1056/NEJM199905273402104  0.92
1999 Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 38: 5362-77. PMID 10220323 DOI: 10.1021/bi982878x  0.92
1999 Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, Nguyen HO, Heinrich C, Torchia M, Safar J, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice. Cell. 96: 869-78. PMID 10102274  0.92
1999 Viles JH, Cohen FE, Prusiner SB, Goodin DB, Wright PE, Dyson HJ. Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proceedings of the National Academy of Sciences of the United States of America. 96: 2042-7. PMID 10051591  0.96
1999 Harrison PM, Chan HS, Prusiner SB, Cohen FE. Thermodynamics of model prions and its implications for the problem of prion protein folding. Journal of Molecular Biology. 286: 593-606. PMID 9973573 DOI: 10.1006/jmbi.1998.2497  0.96
1999 Wille H, Prusiner SB. Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions. Biophysical Journal. 76: 1048-62. PMID 9916037 DOI: 10.1016/S0006-3495(99)77270-X  0.6
1998 Safar J, Prusiner SB. Molecular studies of prion diseases. Progress in Brain Research. 117: 421-34. PMID 9932423  0.76
1998 Post K, Pitschke M, Schäfer O, Wille H, Appel TR, Kirsch D, Mehlhorn I, Serban H, Prusiner SB, Riesner D. Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation. Biological Chemistry. 379: 1307-17. PMID 9865603  0.6
1998 Lee IY, Westaway D, Smit AF, Wang K, Seto J, Chen L, Acharya C, Ankener M, Baskin D, Cooper C, Yao H, Prusiner SB, Hood LE. Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Research. 8: 1022-37. PMID 9799790  0.92
1998 Safar J, Wille H, Itri V, Groth D, Serban H, Torchia M, Cohen FE, Prusiner SB. Eight prion strains have PrP(Sc) molecules with different conformations. Nature Medicine. 4: 1157-65. PMID 9771749 DOI: 10.1038/2654  0.96
1998 Tremblay P, Meiner Z, Galou M, Heinrich C, Petromilli C, Lisse T, Cayetano J, Torchia M, Mobley W, Bujard H, DeArmond SJ, Prusiner SB. Doxycycline control of prion protein transgene expression modulates prion disease in mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 12580-5. PMID 9770528 DOI: 10.1073/pnas.95.21.12580  0.92
1998 Baldwin MA, James TL, Cohen FE, Prusiner SB. The three-dimensional structure of prion protein: implications for prion disease. Biochemical Society Transactions. 26: 481-6. PMID 9765900  0.92
1998 Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR. Mapping the prion protein using recombinant antibodies. Journal of Virology. 72: 9413-8. PMID 9765500  0.64
1998 Cohen FE, Prusiner SB. Pathologic conformations of prion proteins. Annual Review of Biochemistry. 67: 793-819. PMID 9759504 DOI: 10.1146/annurev.biochem.67.1.793  0.96
1998 Prusiner SB, Scott MR, DeArmond SJ, Cohen FE. Prion protein biology. Cell. 93: 337-48. PMID 9590169 DOI: 10.1016/S0092-8674(00)81163-0  0.92
1998 Stöckel J, Safar J, Wallace AC, Cohen FE, Prusiner SB. Prion protein selectively binds copper(II) ions. Biochemistry. 37: 7185-93. PMID 9585530 DOI: 10.1021/bi972827k  0.96
1998 Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. A transmembrane form of the prion protein in neurodegenerative disease. Science (New York, N.Y.). 279: 827-34. PMID 9452375 DOI: 10.1126/science.279.5352.827  0.92
1998 DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB. Changes in the localization of brain prion proteins during scrapie infection. Neurology. 50: 1271-80; discussion . PMID 9443448  0.92
1997 Blochberger TC, Cooper C, Peretz D, Tatzelt J, Griffith OH, Baldwin MA, Prusiner SB. Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system. Protein Engineering. 10: 1465-73. PMID 9543009  0.92
1997 Prusiner SB, Scott MR. Genetics of prions. Annual Review of Genetics. 31: 139-75. PMID 9442893 DOI: 10.1146/annurev.genet.31.1.139  0.92
1997 DeArmond SJ, Sánchez H, Yehiely F, Qiu Y, Ninchak-Casey A, Daggett V, Camerino AP, Cayetano J, Rogers M, Groth D, Torchia M, Tremblay P, Scott MR, Cohen FE, Prusiner SB. Selective neuronal targeting in prion disease. Neuron. 19: 1337-48. PMID 9427256 DOI: 10.1016/S0896-6273(00)80424-9  0.92
1997 Scott MR, Safar J, Telling G, Nguyen O, Groth D, Torchia M, Koehler R, Tremblay P, Walther D, Cohen FE, DeArmond SJ, Prusiner SB. Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 14279-84. PMID 9405603 DOI: 10.1073/pnas.94.26.14279  0.92
1997 Donne DG, Viles JH, Groth D, Mehlhorn I, James TL, Cohen FE, Prusiner SB, Wright PE, Dyson HJ. Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible. Proceedings of the National Academy of Sciences of the United States of America. 94: 13452-7. PMID 9391046 DOI: 10.1073/pnas.94.25.13452  0.92
1997 Diez M, Koistinaho J, Dearmond SJ, Groth D, Prusiner SB, Hökfelt T. Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease. Proceedings of the National Academy of Sciences of the United States of America. 94: 13267-72. PMID 9371835  0.64
1997 Scott MR, Groth D, Tatzelt J, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Propagation of prion strains through specific conformers of the prion protein. Journal of Virology. 71: 9032-44. PMID 9371560  0.92
1997 Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James TL, Houghten RA, Cohen FE, Prusiner SB, Burton DR. A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. Journal of Molecular Biology. 273: 614-22. PMID 9356250 DOI: 10.1006/jmbi.1997.1328  0.92
1997 Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB. A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. Journal of Virology. 71: 8821-31. PMID 9343242  0.92
1997 James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 94: 10086-91. PMID 9294167 DOI: 10.1073/pnas.94.19.10086  0.92
1997 Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James TL, Cohen FE, Prusiner SB. Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proceedings of the National Academy of Sciences of the United States of America. 94: 10069-74. PMID 9294164 DOI: 10.1073/pnas.94.19.10069  0.92
1997 Kaneko K, Wille H, Mehlhorn I, Zhang H, Ball H, Cohen FE, Baldwin MA, Prusiner SB. Molecular properties of complexes formed between the prion protein and synthetic peptides. Journal of Molecular Biology. 270: 574-86. PMID 9245588 DOI: 10.1006/jmbi.1997.1135  0.96
1997 Muramoto T, DeArmond SJ, Scott M, Telling GC, Cohen FE, Prusiner SB. Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix. Nature Medicine. 3: 750-5. PMID 9212101 DOI: 10.1038/nm0797-750  0.92
1997 Lundberg KM, Stenland CJ, Cohen FE, Prusiner SB, Millhauser GL. Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR. Chemistry & Biology. 4: 345-55. PMID 9195875  0.92
1997 Yehiely F, Bamborough P, Da Costa M, Perry BJ, Thinakaran G, Cohen FE, Carlson GA, Prusiner SB. Identification of candidate proteins binding to prion protein. Neurobiology of Disease. 3: 339-55. PMID 9173930 DOI: 10.1006/nbdi.1997.0130  0.92
1997 Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James TL, Cohen FE. Physical studies of conformational plasticity in a recombinant prion protein. Biochemistry. 36: 3543-53. PMID 9132005 DOI: 10.1021/bi961965r  0.92
1997 Kaneko K, Vey M, Scott M, Pilkuhn S, Cohen FE, Prusiner SB. COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 94: 2333-8. PMID 9122195  0.96
1997 Telling GC, Tremblay P, Torchia M, Dearmond SJ, Cohen FE, Prusiner SB. N-terminally tagged prion protein supports prion propagation in transgenic mice. Protein Science : a Publication of the Protein Society. 6: 825-33. PMID 9098892 DOI: 10.1002/pro.5560060409  0.92
1997 Carlson GA, Banks S, Lund D, Reichert C, Groth D, Torchia M, Dearmond SJ, Prusiner SB. Failure to transmit disease from gray tremor mutant mice. Journal of Virology. 71: 2342-5. PMID 9032370  0.64
1997 Harrison PM, Bamborough P, Daggett V, Prusiner SB, Cohen FE. The prion folding problem. Current Opinion in Structural Biology. 7: 53-9. PMID 9032055 DOI: 10.1016/S0959-440X(97)80007-3  0.92
1997 Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. Prion protein gene variation among primates. Journal of Molecular Biology. 265: 257. PMID 9020986 DOI: 10.1006/jmbi.1996.0791  0.96
1996 DeArmond SJ, Qiu Y, Wong K, Nixon R, Hyun W, Prusiner SB, Mobley WC. Abnormal plasma membrane properties and functions in prion-infected cell lines. Cold Spring Harbor Symposia On Quantitative Biology. 61: 531-40. PMID 9246479  0.92
1996 Bamborough P, Wille H, Telling GC, Yehiely F, Prusiner SB, Cohen FE. Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations. Cold Spring Harbor Symposia On Quantitative Biology. 61: 495-509. PMID 9246476  0.92
1996 Huang Z, Prusiner SB, Cohen FE. Scrapie prions: a three-dimensional model of an infectious fragment. Folding & Design. 1: 13-9. PMID 9079359 DOI: 10.1016/S1359-0278(96)00007-7  0.96
1996 Muramoto T, Scott M, Cohen FE, Prusiner SB. Recombinant scrapie-like prion protein of 106 amino acids is soluble. Proceedings of the National Academy of Sciences of the United States of America. 93: 15457-62. PMID 8986833  0.96
1996 Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A, Prusiner SB. Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proceedings of the National Academy of Sciences of the United States of America. 93: 14945-9. PMID 8962161 DOI: 10.1073/pnas.93.25.14945  0.92
1996 Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science (New York, N.Y.). 274: 2079-82. PMID 8953038 DOI: 10.1126/science.274.5295.2079  0.92
1996 Wille H, Baldwin MA, Cohen FE, DeArmond SJ, Prusiner SB. Prion protein amyloid: separation of scrapie infectivity from PrP polymers. Ciba Foundation Symposium. 199: 181-99; discussion 1. PMID 8915611  0.96
1996 Mastrianni JA, Iannicola C, Myers RM, DeArmond S, Prusiner SB. Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease. Neurology. 47: 1305-12. PMID 8909447  0.92
1996 Diez M, Koistinaho J, DeArmond SJ, Camerino AP, Groth D, Caytano JC, Prusiner SB, Hökfelt T. Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice. Neuroreport. 7: 1887-92. PMID 8905686  0.64
1996 Heller J, Kolbert AC, Larsen R, Ernst M, Bekker T, Baldwin M, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR studies of the prion protein H1 fragment. Protein Science : a Publication of the Protein Society. 5: 1655-61. PMID 8844854 DOI: 10.1002/pro.5560050819  0.92
1996 Wong K, Qiu Y, Hyun W, Nixon R, VanCleff J, Sanchez-Salazar J, Prusiner SB, DeArmond SJ. Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release. Neurology. 47: 741-50. PMID 8797473  0.64
1996 Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB. Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein. Neurology. 47: 449-53. PMID 8757019  0.64
1996 Telling GC, Haga T, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes & Development. 10: 1736-50. PMID 8698234  0.92
1996 Williamson RA, Peretz D, Smorodinsky N, Bastidas R, Serban H, Mehlhorn I, DeArmond SJ, Prusiner SB, Burton DR. Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 7279-82. PMID 8692983  0.64
1996 Wille H, Zhang GF, Baldwin MA, Cohen FE, Prusiner SB. Separation of scrapie prion infectivity from PrP amyloid polymers. Journal of Molecular Biology. 259: 608-21. PMID 8683568 DOI: 10.1006/jmbi.1996.0343  0.96
1996 Lledo PM, Tremblay P, DeArmond SJ, Prusiner SB, Nicoll RA. Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 93: 2403-7. PMID 8637886 DOI: 10.1073/pnas.93.6.2403  0.92
1996 Riesner D, Kellings K, Post K, Wille H, Serban H, Groth D, Baldwin MA, Prusiner SB. Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity. Journal of Virology. 70: 1714-22. PMID 8627692  0.72
1996 Mehlhorn I, Groth D, Stöckel J, Moffat B, Reilly D, Yansura D, Willett WS, Baldwin M, Fletterick R, Cohen FE, Vandlen R, Henner D, Prusiner SB. High-level expression and characterization of a purified 142-residue polypeptide of the prion protein. Biochemistry. 35: 5528-37. PMID 8611544 DOI: 10.1021/bi952965e  0.96
1996 Huang Z, Prusiner SB, Cohen FE. Structures of prion proteins and conformational models for prion diseases. Current Topics in Microbiology and Immunology. 207: 49-67. PMID 8575206  0.96
1996 DeArmond SJ, Prusiner SB. Transgenetics and neuropathology of prion diseases. Current Topics in Microbiology and Immunology. 207: 125-46. PMID 8575201  0.64
1995 Kazmirski SL, Alonso DO, Cohen FE, Prusiner SB, Daggett V. Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation. Chemistry & Biology. 2: 305-15. PMID 9383432 DOI: 10.1016/1074-5521(95)90049-7  0.92
1995 Huang Z, Prusiner SB, Cohen FE. Scrapie prions: a three-dimensional model of an infectious fragment. Folding & Design. 1: 13-9. PMID 9162135  0.96
1995 Wiese U, Wulfert M, Prusiner SB, Riesner D. Scanning for mutations in the human prion protein open reading frame by temporal temperature gradient gel electrophoresis. Electrophoresis. 16: 1851-60. PMID 8586053  0.48
1995 Spudich S, Mastrianni JA, Wrensch M, Gabizon R, Meiner Z, Kahana I, Rosenmann H, Kahana E, Prusiner SB. Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene. Molecular Medicine (Cambridge, Mass.). 1: 607-13. PMID 8529127  0.92
1995 Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. Prion protein gene variation among primates. Journal of Molecular Biology. 245: 362-74. PMID 7837269  0.96
1995 DeArmond SJ, Prusiner SB. Prion protein transgenes and the neuropathology in prion diseases. Brain Pathology (Zurich, Switzerland). 5: 77-89. PMID 7767493  0.64
1995 DeArmond SJ, Prusiner SB. Etiology and pathogenesis of prion diseases. The American Journal of Pathology. 146: 785-811. PMID 7717447  0.64
1995 Tatzelt J, Zuo J, Voellmy R, Scott M, Hartl U, Prusiner SB, Welch WJ. Scrapie prions selectively modify the stress response in neuroblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 2944-8. PMID 7708753  0.48
1995 Nguyen J, Baldwin MA, Cohen FE, Prusiner SB. Prion protein peptides induce alpha-helix to beta-sheet conformational transitions. Biochemistry. 34: 4186-92. PMID 7703230  0.44
1995 Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D. Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. The Journal of Cell Biology. 129: 121-32. PMID 7698979  0.48
1995 Baldwin MA, Cohen FE, Prusiner SB. Prion protein isoforms, a convergence of biological and structural investigations. The Journal of Biological Chemistry. 270: 19197-200. PMID 7642588  0.96
1995 Westaway D, Carlson GA, Prusiner SB. On safari with PrP: prion diseases of animals. Trends in Microbiology. 3: 141-7. PMID 7613755 DOI: 10.1016/S0966-842X(00)88903-9  0.92
1995 Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA. X-ray diffraction of scrapie prion rods and PrP peptides. Journal of Molecular Biology. 252: 412-22. PMID 7563061 DOI: 10.1006/jmbi.1995.0507  0.92
1995 Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell. 83: 79-90. PMID 7553876 DOI: 10.1016/0092-8674(95)90236-8  0.92
1995 Raeber AJ, Muramoto T, Kornberg TB, Prusiner SB. Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster. Mechanisms of Development. 51: 317-27. PMID 7547477 DOI: 10.1016/0925-4773(95)00379-7  0.92
1995 Zhang H, Kaneko K, Nguyen JT, Livshits TL, Baldwin MA, Cohen FE, James TL, Prusiner SB. Conformational transitions in peptides containing two putative alpha-helices of the prion protein. Journal of Molecular Biology. 250: 514-26. PMID 7542350 DOI: 10.1006/jmbi.1995.0395  0.92
1995 Mastrianni JA, Curtis MT, Oberholtzer JC, Da Costa MM, DeArmond S, Prusiner SB, Garbern JY. Prion disease (PrP-A117V) presenting with ataxia instead of dementia. Neurology. 45: 2042-50. PMID 7501157  0.92
1995 Kaneko K, Peretz D, Pan KM, Blochberger TC, Wille H, Gabizon R, Griffith OH, Cohen FE, Baldwin MA, Prusiner SB. Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 92: 11160-4. PMID 7479957 DOI: 10.1073/pnas.92.24.11160  0.92
1994 Jefferys JG, Empson RM, Whittington MA, Prusiner SB. Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones. Neurobiology of Disease. 1: 25-30. PMID 9216983 DOI: 10.1006/nbdi.1994.0004  0.92
1994 Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson GA, Prusiner SB. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell. 76: 117-29. PMID 8287472  0.64
1994 Prusiner SB, DeArmond SJ. Prion diseases and neurodegeneration. Annual Review of Neuroscience. 17: 311-39. PMID 8210178 DOI: 10.1146/annurev.ne.17.030194.001523  0.64
1994 Prusiner SB, Hsiao KK. Human prion diseases. Annals of Neurology. 35: 385-95. PMID 8154865 DOI: 10.1002/ana.410350404  0.92
1994 Taraboulos A, Scott M, Semenov A, Avrahami D, Prusiner SB. Biosynthesis of the prion proteins in scrapie-infected cells in culture. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 27: 303-7. PMID 8081243  0.48
1994 Fink JK, Peacock ML, Warren JT, Roses AD, Prusiner SB. Detecting prion protein gene mutations by denaturing gradient gel electrophoresis. Human Mutation. 4: 42-50. PMID 7951257 DOI: 10.1002/humu.1380040106  0.92
1994 Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB. Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 9936-40. PMID 7937921 DOI: 10.1073/pnas.91.21.9936  0.92
1994 Hsiao KK, Groth D, Scott M, Yang SL, Serban H, Rapp D, Foster D, Torchia M, Dearmond SJ, Prusiner SB. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 9126-30. PMID 7916462  0.64
1994 Kellings K, Prusiner SB, Riesner D. Nucleic acids in prion preparations: unspecific background or essential component? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 425-30. PMID 7913761 DOI: 10.1098/rstb.1994.0039  0.48
1994 DeArmond SJ, Yang SL, Cayetano-Canlas J, Groth D, Prusiner SB. The neuropathological phenotype in transgenic mice expressing different prion protein constructs. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 415-23. PMID 7913760 DOI: 10.1098/rstb.1994.0038  0.64
1994 Gabizon R, Rosenman H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB. Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 385-90. PMID 7913755 DOI: 10.1098/rstb.1994.0033  0.92
1994 Carlson GA, DeArmond SJ, Torchia M, Westaway D, Prusiner SB. Genetics of prion diseases and prion diversity in mice. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 363-9. PMID 7913753 DOI: 10.1098/rstb.1994.0030  0.64
1994 Huang Z, Gabriel JM, Baldwin MA, Fletterick RJ, Prusiner SB, Cohen FE. Proposed three-dimensional structure for the cellular prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 7139-43. PMID 7913747 DOI: 10.1073/pnas.91.15.7139  0.92
1994 De Fea KA, Nakahara DH, Calayag MC, Yost CS, Mirels LF, Prusiner SB, Lingappa VR. Determinants of carboxyl-terminal domain translocation during prion protein biogenesis. The Journal of Biological Chemistry. 269: 16810-20. PMID 7911469  0.92
1994 Carlson GA, Ebeling C, Yang SL, Telling G, Torchia M, Groth D, Westaway D, DeArmond SJ, Prusiner SB. Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 5690-4. PMID 7911243  0.64
1994 Gomi H, Ikeda T, Kunieda T, Itohara S, Prusiner SB, Yamanouchi K. Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats. Neuroscience Letters. 166: 171-4. PMID 7909925 DOI: 10.1016/0304-3940(94)90478-2  0.92
1994 Cohen FE, Pan KM, Huang Z, Baldwin M, Fletterick RJ, Prusiner SB. Structural clues to prion replication. Science (New York, N.Y.). 264: 530-1. PMID 7909169  0.92
1993 Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proceedings of the National Academy of Sciences of the United States of America. 90: 10608-12. PMID 7902565  0.64
1993 Borchelt DR, Rogers M, Stahl N, Telling G, Prusiner SB. Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology. 3: 319-29. PMID 7691278 DOI: 10.1093/glycob/3.4.319  0.92
1992 Taraboulos A, Raeber AJ, Borchelt DR, Serban D, Prusiner SB. Synthesis and trafficking of prion proteins in cultured cells. Molecular Biology of the Cell. 3: 851-63. PMID 1356522  0.92
1992 Raeber AJ, Borchelt DR, Scott M, Prusiner SB. Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems. Journal of Virology. 66: 6155-63. PMID 1356161  0.56
1992 Borchelt DR, Taraboulos A, Prusiner SB. Evidence for synthesis of scrapie prion proteins in the endocytic pathway. The Journal of Biological Chemistry. 267: 16188-99. PMID 1353761  0.92
1990 Taraboulos A, Rogers M, Borchelt DR, McKinley MP, Scott M, Serban D, Prusiner SB. Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 87: 8262-6. PMID 1978322  0.92
1990 Stahl N, Borchelt DR, Prusiner SB. Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. Biochemistry. 29: 5405-12. PMID 1974460  0.92
1990 Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB. Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. The Journal of Cell Biology. 110: 743-52. PMID 1968466  0.92
1988 Butler DA, Scott MR, Bockman JM, Borchelt DR, Taraboulos A, Hsiao KK, Kingsbury DT, Prusiner SB. Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. Journal of Virology. 62: 1558-64. PMID 3282080  0.92
1987 Stahl N, Borchelt DR, Hsiao K, Prusiner SB. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell. 51: 229-40. PMID 2444340 DOI: 10.1016/0092-8674(87)90150-4  0.92
1970 Lindberg O, Prusiner SB, Cannon B, Ching TM, Eisenhardt RH. Metabolic control in isolated brown fat cells. Lipids. 5: 204-9. PMID 4314248 DOI: 10.1007/BF02532470  0.92
1968 Prusiner SB, Cannon B, Lindberg O. Oxidative metabolism in cells isolated from brown adipose tissue. 1. Catecholamine and fatty acid stimulation of respiration. European Journal of Biochemistry / Febs. 6: 15-22. PMID 5725810  0.92
1968 Prusiner SB, Cannon B, Ching TM, Lindberg O. Oxidative metabolism in cells isolated from brown adipose tissue. 2. Catecholamine regulated respiratory control. European Journal of Biochemistry / Febs. 7: 51-7. PMID 5707712  0.92
1968 Prusiner SB, Eisenhardt RH, Rylander E, Lindberg O. The regulation of oxidative metabolism of isolated brown fat cells. Biochemical and Biophysical Research Communications. 30: 508-15. PMID 5645437  0.92
Show low-probability matches.